BIO-RAD MCA711A647 Rat anti Mouse CD11b antibody, clone 5C6,Rat anti Mouse CD11b antibody, clone 5C6-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

BIO-RAD MCA711A647 Rat anti Mouse CD11b antibody, clone 5C6,Rat anti Mouse CD11b antibody, clone 5C6

2024-10-22

Rat anti Mouse CD11b antibody, clone 5C6

货号：MCA711A647

规格：100 Tests/1ml

价格：3162

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD11b

物种：小鼠

宿主：大鼠

抗体亚型：IgG2b

克隆号：5C6

荧光染料：Alexa Fluor 647

产品介绍
Rat anti Mouse CD11b antibody, clone 5C6recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles.Rat anti Mouse CD11b antibody, clone 5C6 immunoprecipitates a heterodimer of ~165 and ~95 kDa. This clone also exhibits various functional properties, reportedly inhibiting adhesionin vitroand inflammatory recruitmentin vivo. Rat anti Mouse CD11b antibody, clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.
产品详情
Target Species	Mouse
Product Form	Purified IgG conjugated to Alexa Fluor 647 - liquid
Preparation	Purified IgG prepared by ion exchange chromatography
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09% Sodium Azide (NaN3)1% Bovine Serum Albumin
Immunogen	Thioglycollate-elicited peritoneal macrophages (TPM)
Approx. Protein Concentrations	IgG concentration 0.05 mg/ml
Max Ex/Em	Fluorophore	Excitation Max (nm)	Emission Max (nm)
Alexa Fluor®647	650	665
Acknowledgements	This product is provided under an intellectual property licence from Life Technologies Corporation. The transfer of this product is contingent on the buyer using the purchased product solely in research, excluding contract research or any fee for service research, and the buyer must not sell or otherwise transfer this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; (c) manufacturing or quality assurance or quality control, or (d) resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad CA 92008 USA or outlicensing@thermofisher.com
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	Neat
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Dohi, K.et al.(2010) Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury.J Neuroinflammation. 7: 41.2.Engwerda, C.R.et al.(2002) Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria.J Exp Med. 195: 1371-7.3.Heneka, M.T.et al.(2010) Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.Proc Natl Acad Sci U S A. 107: 6058-63.4.Kim, D.et al.(2010) NADPH oxidase 2-derived reactive oxygen species in spinal cord microglia contribute to peripheral nerve injury-induced neuropathic pain.Proc Natl Acad Sci U S A. 107: 14851-6.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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BIO-RAD MCA711A647 Rat anti Mouse CD11b antibody, clone 5C6,Rat anti Mouse CD11b antibody, clone 5C6

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