BIO-RAD MCA4710GA CD253 antibody | N2B2,CD253 antibody | N2B2

2024-10-22

CD253 antibody | N2B2

货号:MCA4710GA

规格:0.1 mg

价格:2023

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:CD253

物种:小鼠

宿主:大鼠

抗体亚型:IgG1, kappa

荧光染料:其它

产品介绍
Rat anti Mouse CD253 antibody, clone N2B2recognizes mouse CD253, also known as TNF-related apoptosis-inducing ligand or TRAIL, a member of the tumour necrosis factor ligand superfamily. When bound to the death receptors DR4 and DR5 caspase-8-dependent apoptosis is induced. However, CD253 might also be bound by the decoy receptor DcR1 which cannot induce apoptosis, and DcR2 which activates NF-kappa-B.Rat anti Mouse CD253 antibody, clone N2B2 has been reported to block NK cell cytotoxicityin vitro(Kayagakiet al.1999).
产品详情
Target SpeciesMouse
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography
Buffer SolutionPhosphate buffered saline
ImmunogenMouse CD253-transfected 2PK-3 cells.
Preservative Stabilisers<0.1% Sodium Azide (NaN3)
Approx. Protein ConcentrationsIgG concentration 0.5mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow Cytometry1/20
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Kayagaki, N.et al.(1999) Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells.J Immunol. 163 (4): 1906-13.

技术参数

产品应用 Flow

产品类型 单克隆抗体

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