Bio-Rad 人 INI-1:Preservative Free MCA3457Z,mouse anti human INI-1:Preservative Free

2024-10-22

mouse anti human INI-1:Preservative Free

货号:MCA3457Z

规格:0.1 mg

价格:7676

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:INI-1

物种:人

宿主:小鼠

抗体亚型:IgG1

克隆号:3E10

荧光染料:Preservative Free

产品介绍
Mouse anti Human INI-1 antibody, clone 3E10recognizes human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, also known as INI-1, BRG1-associated factor 47, BAF47, SMARCB1, Integrase interactor 1 protein or SNF5 homolog. INI-1 is a 385 amino acid ~46 kDa component of the BAF complex involved in chromatin remodelling. INI-1 also acts as a tumor supressor.Mutations in the SMARCB1 gene can lead to hereditary cancer syndromes including Rhabdoid tumor predisposition syndrome 1 (RTPS1) with presentation of renal or nervous system tumors or Schwannomatosis 1 (SWNTS1) with development of non-vestibular Schwannomas. Mutation in the SMARCB1 gene can also lead to Mental retardation, autosomal dominant 15 (MRD15) characterized by multiple developmental anomalies, mental retardation and hearing loss (Tsurusakiet al.2012).
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein A from ascites
Buffer SolutionPhosphate buffered saline
ImmunogenRecombinant protein corresponding to aa 81-181 of human INI-1
Preservative StabilisersNone present
Approx. Protein ConcentrationsIgG concentration 0.5mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store at -20℃ only.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting0.1
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 IHC(P); WB

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