BIO-RAD MCA4706 Rat anti Mouse CD105,Rat anti Mouse CD105-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

BIO-RAD MCA4706 Rat anti Mouse CD105,Rat anti Mouse CD105

2024-10-22

Rat anti Mouse CD105

货号：MCA4706

规格：0.25 mg

价格：3043

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：CD105

物种：小鼠

宿主：大鼠

抗体亚型：IgG1, kappa

荧光染料：其它

产品介绍
Rat anti Mouse CD105 antibody, clone MJ7/18recognizes mouse CD105, also known as Endoglin, a cell surface glycoprotein member of the TGF beta receptor complex. CD105 is a homodimer that forms a heteromeric complex with TGF beta receptors I and/or II. The complex binds TGF beta 1 and 3 efficiently, and TGF beta 2 less efficiently. It may also play a role in the binding of endothelial cells to integrins and cytoskeletal organisation. It is involved in cardiovascular development. CD105 is expressed on endothelial cells in all tissues except bone marrow and in also found in stromal cells within the connective tissue of the intestine, stomach and heart. It may be a useful marker for proliferating endothelium in tumours.
产品详情
Target Species	Mouse
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography
Buffer Solution	Phosphate buffered saline
Immunogen	Inflamed mouse skin.
Preservative Stabilisers	<0.1% Sodium Azide (NaN3)
Approx. Protein Concentrations	IgG concentration 0.5mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	1/10
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Ge, A.Z. & Butcher, E.C. (1994) Cloning and expression of a cDNA encoding mouse endoglin, an endothelial cell TGF-beta ligand.Gene. 138 (1-2): 201-6.2.Hallmann, R.et al.(1995) Novel mouse endothelial cell surface marker is suppressed during differentiation of the blood brain barrier.Dev Dyn. 202 (4): 325-32.3.Bredow, S.et al.(2000) Imaging of tumour neovasculature by targeting the TGF-beta binding receptor endoglin.Eur J Cancer. 36 (5): 675-81.4.Leguerney, I.et al.(2015) Molecular ultrasound imaging using contrast agents targeting endoglin, vascular endothelial growth factor receptor 2 and integrin.Ultrasound Med Biol. 41 (1): 197-207.

技术参数

产品应用 Flow

产品类型单克隆抗体

推荐用于 Flow

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BIO-RAD MCA4706 Rat anti Mouse CD105,Rat anti Mouse CD105

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