Bio-Rad 人UBE3A:Preservative Free MCA3532Z,mouse anti human UBE3A:Preservative Free-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad 人UBE3A:Preservative Free MCA3532Z,mouse anti human UBE3A:Preservative Free

2024-10-22

mouse anti human UBE3A:Preservative Free

货号：MCA3532Z

规格：0.1 mg

价格：7676

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：UBE3A

物种：人

宿主：小鼠

抗体亚型：IgG2a

克隆号：2F6

荧光染料：Preservative Free

产品介绍
Mouse anti Human UBE3A antibody, clone 2F6recognizes human Ubiquitin-protein ligase E3A, also known as UBE3A, E6AP ubiquitin-protein ligase, Human papillomavirus E6-associated protein, Oncogenic protein-associated protein E6-AP or Renal carcinoma antigen NY-REN-54. UBE3A is an 875 amino acid ~95 kDa E3 ubiquitin-protein ligase.Mutations of the UBE3A gene can lead to the development of Angelman syndrome (AS) a neurodevelopmental disorder characterized by by severe motor and intellectual retardation, hypotonia, ataxia and jerky limb movements (Sadikovicet al.2014).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A from ascites
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	None present
Immunogen	Recombinant protein corresponding to aa 51-151 of human UBE3A
Approx. Protein Concentrations	Ig concentration 0.5 mg/ml
Fusion Partners	Spleen cells from immunized Balb/c mice were fused with cells from the Sp2/0 myeloma cell line.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store at -20℃ only.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
Immunofluorescence	√	0.1
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Wolyniec, K.et al.(2012) E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis.Blood. 120: 822-32.2.Paul, P.J.et al.(2016) Restoration of tumor suppression in prostate cancer by targeting the E3 ligase E6AP.Oncogene. 35 (48): 6235-45.

技术参数

产品应用 IF;IHC(P);WB

产品类型单克隆抗体

推荐用于 IF;IHC(P);WB

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Bio-Rad 人UBE3A:Preservative Free MCA3532Z,mouse anti human UBE3A:Preservative Free

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