Bio-Rad mouse anti human C4BP MCA2609,mouse anti human C4BP

2024-10-22

mouse anti human C4BP

货号:MCA2609

规格:0.1 mg

价格:5695

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:C4BP

物种:人

宿主:小鼠

抗体亚型:IgG2b

克隆号:051-198.6.3 (10-07)

荧光染料:Purified

产品介绍
Mouse anti human C4bp monoclonal antibody, clone 051-198.6.3 (10-07), recognizes complement component 4 binding protein (C4bp). There are three variants of C4bp, composed of alpha and beta chains. The predominant form is a 570 kDa complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain.C4bp regulates the activation of the classical complement pathway. It is a cofactor to the C3b/C4b inactivator, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b. C4bp also regulates the C4bC2a complex (C3 convertase), accelerating its degradation by dissociating the complement fragment C2a.Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S. C4bp is expressed in the blood serum.
产品详情
Target SpeciesHuman
Product FormPurified Ig - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein A from ascites
Buffer SolutionBorate buffered saline
ImmunogenNative human C4 binding protein.
Approx. Protein ConcentrationsIgG concentration 1.04 mg/ml
Preservative Stabilisers0.1% Sodium Azide (NaN3)
RegulatoryFor research purposes only
GuaranteeGuaranteed until date of expiry. Please see product label.
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application NameVerifiedMin DilutionMax Dilution
ELISA
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Huang, S.et al.(2016) Reciprocal relationship between contact and complement system activation on artificial polymers exposed to whole human bloodBiomaterials. 77: 111-9.

技术参数

产品应用 ELISA

产品类型 单克隆抗体

推荐用于 ELISA

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