BIO-RAD MCA2519GA Mouse anti Human CD206 antibody, clone 7-450,Mouse anti Human CD206 antibody, clone 7-450-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

BIO-RAD MCA2519GA Mouse anti Human CD206 antibody, clone 7-450,Mouse anti Human CD206 antibody, clone 7-450

2024-10-22

Mouse anti Human CD206 antibody, clone 7-450

货号：MCA2519GA,MCA2519

规格：0.2 mg,0.2 mg

价格：2015,3740

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：CD206

物种：人

宿主：小鼠

抗体亚型：IgG2a

克隆号：7-450

荧光染料：Purified

产品介绍
Mouse anti Human CD206 antibody, clone 7-450recognizes human CD206, otherwise known as macrophage mannose receptor (MMR), a transmembrane protein and member of the multilectin family of pattern recognition receptors (PRRs), which mediates phagocytosis and endocytosis, and is modulated by a range of factors including cytokines, immunoglobulin receptors and pathogens.CD206 has two extracellular lectin binding sites: the cysteine-rich domain binds to sulphated sugars of glycoproteins such as thyroid stimulating hormone, whilst the recognition of mannose and fucose occurs through carbohydrate recognition domains (CRDs). The widespread distribution and recognition of a wide range of antigens by macrophages, plays a key role in both innate and adaptive immunity, with CD206 able to bind to both gram-negative and gram-positive bacteria, mycobacterium, yeasts, fungi and parasites. The expression of CD206 is not restricted to macrophages, but is also present on immature dendritic cells (DCs), endothelial cells, kidney mesangial cells, retinal pigment epithelium and tracheal smooth muscle cells.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer Solution	Phosphate buffered saline
Immunogen	Monocyte-derived dendritic cells.
Preservative Stabilisers	0.09% Sodium Azide (NaN3)
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	1/50
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Stahl, P.D. & Ezekowitz, R.A. (1998) The mannose receptor is a pattern recognition receptor involved in host defense.Curr Opin Immunol. 10 (1): 50-5.2.Gordon, S. (1995) The macrophage.Bioessays. 17 (11): 977-86.

技术参数

产品应用 IHC

产品类型 Monoclonal Antibody

推荐用于 IHC

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BIO-RAD MCA2519GA Mouse anti Human CD206 antibody, clone 7-450,Mouse anti Human CD206 antibody, clone 7-450

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