Bio-Rad C3a Receptor MCA2455GA,Mouse anti Human C3a Receptor-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad C3a Receptor MCA2455GA,Mouse anti Human C3a Receptor

2024-10-22

Mouse anti Human C3a Receptor

货号：MCA2455GA

规格：0.1 mg

价格：2015

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：C3a Receptor

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：hC3aRZ1

荧光染料：Purified

产品介绍
Mouse anti Human C3a Receptor antibody, clone hC3aRZ1recognizes the receptor for human complement component C3a (C3aR), a ~55 kDa cell surface protein of the rhodopsin family of G protein-coupled seven-transmembrane receptors. C3a is an anaphylatoxin, which is a potent proinflammatory mediator that possesses immunoregulatory properties. C3a regulates inflammatory functions by binding to the C3a receptor. C3aR is expressed on various tissues and leucocytes including basophils, neutrophils, mast cells, eosinophils and activated T lymphocytes.Expression levels of C3aR on human cells varies significantly between donors.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Immunogen	Recombinant human C3aR protein.
Buffer Solution	Phosphate buffered saline
Carrier Free	Yes
Fusion Partners	Cells from immunised BALB/c mice were fused with cells of the X63-Ag8.653 myeloma cell line.
Approx. Protein Concentrations	IgG concentration 1.0 mg/ml
Preservative Stabilisers	0.09%Sodium Azide
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	1/10
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Werfel, T.et al.(2000) Activated human T lymphocytes express a functional C3a receptor.J Immunol. 165 (11): 6599-605.2.Soruri, A.et al.(2003) IL-4 down-regulates anaphylatoxin receptors in monocytes and dendritic cells and impairs anaphylatoxin-induced migrationin vivo.J Immunol. 170 (6): 3306-14.3.Zwirner, J.et al.(1999) Evaluation of C3a receptor expression on human leucocytes by the use of novel monoclonal antibodies.Immunology. 97: 166-72.3.Kacani, L.et al.(2001) C5a and C5a(desArg) enhance the susceptibility of monocyte-derived macrophages to HIV infection.J Immunol. 166: 3410-5.4.Raby, A.C.et al.(2009) Soluble TLR2 reduces inflammation without compromising bacterial clearance by disrupting TLR2 triggering.J Immunol. 183: 506-17.

技术参数

产品应用 IHC(F);Flow

产品类型单克隆抗体

推荐用于 IHC(F);Flow

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Bio-Rad C3a Receptor MCA2455GA,Mouse anti Human C3a Receptor

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