BIO-RAD MCA2504T Mouse anti Human CD44 antibody, clone Bu52,Mouse anti Human CD44 antibody, clone Bu52-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

BIO-RAD MCA2504T Mouse anti Human CD44 antibody, clone Bu52,Mouse anti Human CD44 antibody, clone Bu52

2024-10-22

Mouse anti Human CD44 antibody, clone Bu52

货号：MCA2504T,MCA2504

规格：25 µg,0.2 mg

价格：893,3315

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD44

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：Bu52

荧光染料：Purified

产品介绍
Mouse anti Human CD44 antibody, clone Bu52recognizes the human CD44 cell surface antigen, a ~100 kDa glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and of the breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues. Mouse anti Human CD44 antibody, clone Bu52 recognizes an epitope that is common to all CD44 isoforms.CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer Solution	Phosphate buffered saline
Carrier Free	Yes
Fusion Partners	Cells from immunised mice were fused with cells of the NS0 myeloma cell line
Preservative Stabilisers	0.09%Sodium Azide
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Takahashi, K.et al.(1996) Keratan sulfate modification of CD44 modulates adhesion to hyaluronate.J Biol Chem. 271 (16): 9490-6.2.Belitsos, P.C.et al.(1990) Homotypic cell aggregation induced by anti-CD44(Pgp-1) monoclonal antibodies and related to CD44(Pgp-1) expression.J Immunol. 144 (5): 1661-70.3.Katz, E.et al.(2012) Targeting of Rac GTPases blocks the spread of intact human breast cancer.Oncotarget. 3 (6): 608-19.4.Noda, S.et al.(2019) Effect of cell culture density on dental pulp-derived mesenchymal stem cells with reference to osteogenic differentiation.Sci Rep. 9 (1): 5430.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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BIO-RAD MCA2504T Mouse anti Human CD44 antibody, clone Bu52,Mouse anti Human CD44 antibody, clone Bu52

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