BIO-RAD MCA2059A488 Mouse anti Human CD88 antibody, clone P12/1,Mouse anti Human CD88 antibody, clone P12/1-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

BIO-RAD MCA2059A488 Mouse anti Human CD88 antibody, clone P12/1,Mouse anti Human CD88 antibody, clone P12/1

2024-10-22

Mouse anti Human CD88 antibody, clone P12/1

货号：MCA2059A488

规格：100 Tests/1ml

价格：3162

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD88

物种：人

宿主：小鼠

抗体亚型：IgG2a

克隆号：P12/1

荧光染料：Alexa Fluor 488

产品介绍
Mouse anti Human CD88 antibody, clone P12/1recognizes the C5a receptor (C5aR) also known as CD88 or C5a anaphylatoxin chemotactic receptor 1. CD88 is predominantly expressed on cells of the myeloid lineage.When C5aR is preincubated with C5a, Mouse anti Human CD88 antibody, clone P12/1 does not bind to the receptor, as the binding site of P12/1 is located in the C5a binding region (Werfelet al. 1996andWeinmanet al. 2003)
产品详情
Target Species	Human
Product Form	Purified IgG conjugated to Alexa Fluor 488 - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution	Phosphate buffered saline
Immunogen	C5aR - peptide: Met1- Asn31
Preservative Stabilisers	0.09% Sodium Azide (NaN3)1% Bovine Serum Albumin
Approx. Protein Concentrations	IgG concentration 0.05 mg/ml
Fusion Partners	Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63 - Ag8 myeloma cell line.
Max Ex/Em	Fluorophore	Excitation Max (nm)	Emission Max (nm)
Alexa Fluor®488	495	519
Acknowledgements	This product is provided under an intellectual property licence from Life Technologies Corporation. The transfer of this product is contingent on the buyer using the purchased product solely in research, excluding contract research or any fee for service research, and the buyer must not sell or otherwise transfer this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; (c) manufacturing or quality assurance or quality control, or (d) resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad CA 92008 USA or outlicensing@thermofisher.com
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	Neat
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
推荐产品
Description	Product Code	Applications	Pack Size
Mouse IgG2a Negative Control:Alexa Fluor® 488	MCA929A488	F	100 Tests/1ml
文献
1.Werfel, T.et al. (1996) CD88 antibodies specifically bind to C5aR on dermal CD117+ and CD14+ cells and react with a desmosomal antigen in human skin.J Immunol. 157: 1729-35.2Opperman, M.et al. (1995) Antibodies from the myeloid panel that react with the C5a receptor and anatagonize C5a biological activity.In: Schlossman, S.F. (ed.) Leucocyte Typing V. OUP: 955-6.3.Pollok-Kopp Bet al.(2007) Dynamics of protein kinase C-mediated phosphorylation of the complement C5a receptor on serine 334.J Biol Chem. 282 (7): 4345-53.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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BIO-RAD MCA2059A488 Mouse anti Human CD88 antibody, clone P12/1,Mouse anti Human CD88 antibody, clone P12/1

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