BIO-RAD MCA2042GA Mouse anti Bovine CD63 antibody, clone CC25,Mouse anti Bovine CD63 antibody, clone CC25-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

BIO-RAD MCA2042GA Mouse anti Bovine CD63 antibody, clone CC25,Mouse anti Bovine CD63 antibody, clone CC25

2024-10-22

Mouse anti Bovine CD63 antibody, clone CC25

货号：MCA2042GA

规格：0.1 mg

价格：2185

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD63

物种：Bovine

宿主：小鼠

抗体亚型：IgG1

克隆号：CC25

荧光染料：Purified

产品介绍
Mouse anti Bovine CD63 antibody, clone CC25recognizes the bovine homologue of human CD63, a 237 amino acid multipass transmembrane glycoprotein and member of the tetraspanin TM4SF protein family with a predicted molecular weight of ~26 kDa. CD63 is also known as lysosome associated membrane glycoprotein 3 or LAMP-3.CD63 along with other TM4SF members including CD9, CD61 and CD151 can form specific interactions with phosphoinositide 4-kinase, suggesting a role for CD63 in the recruitment of phosphoinositide 4-kinase to specific membrane sites (Yauch and Hemler 2000). CD63 is expressed on the cell surface of platelets and basophils, along with activated macrophages, monocytes and granulocytes.Mouse anti Bovine CD63, clone CC25 acts as a specific marker for bovine lysozomes and has been used for the identification and quantitation of phagosome-lysozome fusion in models of bacterial insult (Souzaet al.2013).
产品详情
Target Species	Bovine
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09%Sodium Azide
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	1/100
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Brooke, G.P.et al.(1999) Molecular cloning of cattle CD63 and evidence for high level expression on subpopulations of dendritic cells.Immunogenetics. 49 (9): 812-4.2.Colino, J. and Snapper, C.M. (2006) Exosomes from bone marrow dendritic cells pulsed with diphtheria toxoid preferentially induce type 1 antigen-specific IgG responses in naive recipients in the absence of free antigen.J Immunol. 177: 3757-62.3.Souza, C.D.et al.(2007) Role of the mitogen-activated protein kinase pathway in the differential response of bovine monocytes toMycobacterium aviumsubsp. paratuberculosis andMycobacterium aviumsubsp. avium.Microbes Infect. 9: 1545-52.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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BIO-RAD MCA2042GA Mouse anti Bovine CD63 antibody, clone CC25,Mouse anti Bovine CD63 antibody, clone CC25

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