Bio-Rad MCA1227 CD42a抗体,Mouse anti Human CD42a-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad MCA1227 CD42a抗体,Mouse anti Human CD42a

2024-10-22

Mouse anti Human CD42a

货号：MCA1227

规格：0.2 mg

价格：3315

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD42a

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：GRP-P

荧光染料：Purified

产品介绍
Mouse anti Human CD42a antibody, clone GRP-Precognizes the platelet GPIX glycoprotein, a 23kDa surface marker expressed by platelets and megakaryocytes. Platelet GPIX is also known as CD42a.The CD42 complex is the major platelet receptor for von Willebrand factor.
产品详情
Target Species	Human
Species Cross-Reactivity	Target Species	Cross Reactivity
Mink	√
N.B. Antibody reactivity and working conditions may vary between species.
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by ion exchange chromatography
BufferSolution	Phosphate buffered saline
Preservative Stabilisers	0.09% Sodium Azide (NaN3)
Carrier Free	Yes
Immunogen	Human red blood cells and platelets.
Approx. Protein Concentrations	IgG concentration 1.0mg/ml
Fusion Partners	Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Regulatory	For research purposes only
Guarantee	12 monthsfrom date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	1/10	1/100
Immunoprecipitation	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications fromthe originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude itsuse in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. Flow Cytometry Use 10ul of the suggested working dilution to label 10⁶cells or 100ul whole blood
同型
Description	Product Code	Applications	Pack Size
Mouse IgG1 Negative Control	MCA928	F	100 Tests
数据
Staining of human peripheral blood platelets with Mouse anti Human CD42a (MCA1227)
文献
1. Harding, S.A.et al.(2007) Clopidogrel reduces platelet-leucocyte aggregation, monocyte activation and RANTES secretion in type 2 diabetes mellitus.Heart. 92: 1335-7.2. Eisbacher, M.et al.(2001) Inducible expression of the megakaryocyte-specific gene glycoprotein IX is mediated through an Ets binding site and involves upstream activation of extracellular signal-regulated kinase.Cell Growth Differ. 12: 435-45.3. Vettore, S.et al.(2008) Novel point mutation in a leucine-rich repeat of the GPIbalpha chain of the platelet von Willebrand factor receptor, GPIb/IX/V, resulting in an inherited dominant form of Bernard-Soulier syndrome affecting two unrelated families: the N41H variant.Haematologica. 93: 1743-7.4. Fox, S.C.et al.(2004) Quantitation of platelet aggregation and microaggregate formation in whole blood by flow cytometry.Platelets. 15: 85-93.5. Din, J.N.et al.(2010) Effect of moderate walnut consumption on lipid profile, arterial stiffness and platelet activation in humans.Eur J Clin Nutr. 2011 Feb;65(2):234-9.6. Din, J.N.et al.(2008) Dietary intervention with oil rich fish reduces platelet-monocyte aggregation in man.Atherosclerosis. 197: 290-6.7. Schuberth, H.J.et al.(2007) Reactivity of cross-reacting monoclonal antibodies with canine leukocytes, platelets and erythrocytes.Vet Immunol Immunopathol. 119: 47-55.8. Tunströmer, K.et al.(2018) Quantification of Platelet Contractile Movements during Thrombus Formation.Thromb Haemost. 118 (9): 1600-11.9. Jamaly, S.et al.(2018) Elevated plasma levels of P-selectin glycoprotein ligand-1-positive microvesicles in patients with unprovoked venous thromboembolism.J Thromb Haemost. May 31 [Epub ahead of print].

技术参数

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Bio-Rad MCA1227 CD42a抗体,Mouse anti Human CD42a

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