Rat anti Dog CD44 antibody, clone YKIX337.8.7 Thermo ,Rat anti Dog CD44 antibody, clone YKIX337.8.7-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rat anti Dog CD44 antibody, clone YKIX337.8.7 Thermo ,Rat anti Dog CD44 antibody, clone YKIX337.8.7

2024-10-22

Rat anti Dog CD44 antibody, clone YKIX337.8.7

货号：MCA1041GA

规格：0.1 mg

价格：2151

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD44

物种：dog

宿主：大鼠

抗体亚型：IgG2a

克隆号：YKIX337.8.7

荧光染料：Purified

产品介绍
Rat anti Dog CD44 antibody, clone YKIX337.8.7recognizes canine CD44, also known as H-CAM, a single-pass type 1 membrane of approximately 90 kDa expressed by most leucocytes and epithelial cells. CD44 expression is markedly increased upon cell activation (Alldingeret al.2000).CD44 is involved in cell-cell, cell adhesion and cell migration and is the principal cellular receptor for hyaluronate via it'sLINKdomain, additionally CD44 interacts with other ligands including collagens and metalloproteinases.Altered CD44 expression is detected in many forms of invasive and metastatic cancer, CD44 expression has been observed on canine mammary and melanocytic tumors (Serraet al.2004).
产品详情
Target Species	Dog
Species Cross-Reactivity	Target Species	Cross Reactivity
Raccoon	√
N.B. Antibody reactivity and working conditions may vary between species.
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09% Sodium Azide (NaN3)
Immunogen	Concanavilin A activated Canine T cells.
Approx. Protein Concentrations	IgG concentration 1.0 mg/ml
Fusion Partners	Spleen cells from immunised DA rats were fused with cells of the rat Y3/Ag1.2.3.myeloma cell line.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	1/10	1/20
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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文献
1.Cobbold, S. & Metcalfe, S. (1994) Monoclonal antibodies that define canine homologues of human CD antigens: summary of the First International Canine Leukocyte Antigen Workshop (CLAW).Tissue Antigens. 43 (3): 137-54.

技术参数

产品应用 Flow

产品类型单克隆抗体

推荐用于 Flow

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Rat anti Dog CD44 antibody, clone YKIX337.8.7 Thermo ,Rat anti Dog CD44 antibody, clone YKIX337.8.7

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