Rabbit anti Mouse ST2 (N-Terminal) antibody AHP999 bio-rad,Rabbit anti Mouse ST2 (N-Terminal) antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Mouse ST2 (N-Terminal) antibody AHP999 bio-rad,Rabbit anti Mouse ST2 (N-Terminal) antibody

2024-10-22

Rabbit anti Mouse ST2 (N-Terminal) antibody

货号：AHP999

规格：0.1 mg

价格：4990

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原： ST2 (N-Terminal)

物种：小鼠

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Mouse ST2 (N-Terminal) antibodyrecognizes an epitope within the N-Terminal region (NT) of mouse ST2, a member of the Toll-interleukin 1 receptor (TIR) superfamily, expressed by mast cells and TH2helper cells, but not by TH1effector cells.The majority of TIR superfamily members, which includes the Interleukin-1 receptor (IL-1R1), Toll-like receptors (TLRs) and the cytosolic adaptor proteins MyD88, TIRAP, Trif and TRAM, initiate innate immunity through the ultimate activation of the transcription factor NF-kappaB and are inducers of the inflammatory response. In contrast ST2, which itself is unable to activate NF-kappaB, has been identified as a negative regulator of IL-1R1 and TLR4 signaling by sequestering MyD88 and TIRAP in line with its role as a crucial receptor in TH2-cell mediated responses (Brintet al.2004andCoyleet al.1999).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Buffer Solution	Phosphate buffered saline
Antiserum Preparation	Antisera to mouse ST2 (NT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Preservative Stabilisers	0.02% Sodium Azide (NaN3)
Immunogen	A 16 amino acid synthetic peptide located near mouse ST2 amino-terminus. This peptide is common to the three known isoforms of ST2.
Approx. Protein Concentrations	IgG concentration 1.0mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining alquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	1	2.0ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
Description	Product Code	Applications	Pack Size
Goat anti Rabbit IgG (Fc):Biotin	STAR121B	E,WB	1mg
Goat anti Rabbit IgG (H/L):HRP	STAR124P	C,E,WB	1mg
文献
1.Brint, E.K.et al.(2004) ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance.Nat Immunol. 5 (4): 373-9.2.Coyle, A.J.et al.(1999) Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses.J Exp Med. 190 (7): 895-902.

技术参数

产品应用 wb

产品类型多克隆抗体

推荐用于 wb

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Rabbit anti Mouse ST2 (N-Terminal) antibody AHP999 bio-rad,Rabbit anti Mouse ST2 (N-Terminal) antibody

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