Rabbit anti Human caspase-8 antibody AHP967 bio-rad ,Rabbit anti Human caspase-8 antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Human caspase-8 antibody AHP967 bio-rad ,Rabbit anti Human caspase-8 antibody

2024-10-22

Rabbit anti Human caspase-8 antibody

货号：AHP967

规格：0.1 mg

价格：4692

产品类型：免疫组化一抗

品牌：Bio-Rad

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human caspase-8 antibodyrecognizes an epitope within the c-terminal region (CT) of caspase-8, otherwise known as Fas-linked ICE-like protease (FLICE), which shares homology with both Fas-associated via death domain (FADD) and the ICE/Ced-3 family of cysteine proteases.Caspase-8 is classified as an initiator caspase and acts as the most upstream trigger of Fas-Receptor (CD95) and tumour necrosis factor receptor 1 (TNFR1) mediated apoptosis. Upon activation, the cell death receptor Fas, links with the adaptor molecule FADD via corresponding death domains (DD). FADD in turn then binds via death effector domains (DEDs) to procaspase-8, which then undergoes oligomerization and autocatalytic activation.Active Caspase-8 is capable of cleaving all other known caspases, and also cleaves the Bcl-2 family member BH3-interacting domain death agonist (BID), along with the Bcl-2 associated protein p28Bap31 (Wolf & Green 1999).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Antisera to human caspase-8 (CT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.02%Sodium Azide
Immunogen	A 16 amino acid peptide located near the carboxy-terminus of human caspase-8 isoform A.
Approx. Protein Concentrations	IgG concentration 1.0 mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√		0.5ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
Description	Product Code	Applications	Pack Size
Goat anti Rabbit IgG (Fc):Biotin	STAR121B	E,WB	1mg
Goat anti Rabbit IgG (H/L):HRP	STAR124P	C,E,WB	1mg
文献
1.Umezaki, Y.et al.(2011) Blocking synaptic transmission with tetanus toxin light chain reveals modes of neurotransmission in the PDF-positive circadian clock neurons ofDrosophila melanogaster.J Insect Physiol. 57 (9): 1290-9.

技术参数

产品应用 wb

产品类型多克隆抗体

推荐用于 wb

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Rabbit anti Human caspase-8 antibody AHP967 bio-rad ,Rabbit anti Human caspase-8 antibody

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