Rabbit anti caspase-4 (N-terminal) antibody AHP964 bio-rad,Rabbit anti caspase-4 (N-terminal) antibody

2024-10-22

Rabbit anti caspase-4 (N-terminal) antibody

货号:AHP964

规格:0.1 mg

价格:3230

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:caspase-4 (N-terminal)

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti caspase-4 (N-terminal) antibodyrecognizes an epitope within the N-terminal region (NT) of Caspase-4, otherwise known as ICH-2. Caspase-4, a member of the Caspase-1 subfamily of cysteine proteases, exists as an inactive pro-enzyme which undergoes proteolytic cleavage of its p30 precursor form, into smaller p20 and p10 subunits.Caspase-4 is localized to the endoplasmic reticulum (ER) membrane and is involved in response to ER membrane stress in conditions including Alzheimer’s disease and Ischemia and confirms the involvement of Caspase-4 as an instigator of cellular apoptosis.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationAntisera to human Caspase-4 (NT) were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.02%Sodium Azide
ImmunogenA 16 amino acid peptide from human Caspase-4 amino terminus.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Immunohistology - Paraffin12.0ug/ml
Western Blotting1.0ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
DescriptionProduct CodeApplicationsPack Size
Goat anti Rabbit IgG (Fc):BiotinSTAR121BE,WB1mg
Goat anti Rabbit IgG (H/L):HRPSTAR124PC,E,WB1mg
文献
1.Katayama, T.et al.(2004) Induction of neuronal death by ER stress in Alzheimer's disease.J Chem Neuroanat. 28 (1-2): 67-78.

技术参数

产品应用 wb

产品类型 多克隆抗体

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