Goat anti Human GADD34 antibody AHP683 bio-rad,Goat anti Human GADD34 antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Goat anti Human GADD34 antibody AHP683 bio-rad,Goat anti Human GADD34 antibody

2024-10-22

Goat anti Human GADD34 antibody

货号：AHP683

规格：0.1 mg

价格：4310

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：GADD34

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Goat anti Human GADD34 antibodyrecognizes the protein GADD34 (growth arrest and DNA-damage-inducible 34), also known as PPP1R15A. GADD34 is a member of a group of genes whose transcript levels are increased in response to treatment with DNA damaging agents or conditions of stress (Amundsonet al.1998). Induction of GADD34 by ionising radiation has been reported in some cell lines, regardless of p53 status (Hollanderet al.1997). Reports suggest that GADD34 may be involved in a signal transduction pathway controlling cell cycle arrest and/or apoptosis following DNA damage (Hollanderet al.2003).Goat anti human GADD34 antibody has been used successfully for following GADD34 protein turnover in multiple cell lines and primary cells by Western blotting (Zhouet al.2013)
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Antiserum Preparation	Antisera to GADD34 were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution	TRIS buffered saline
Immunogen	Peptide sequence AAALDLSGRRG corresponding to the C-terminus of GADD34 (NP_055145).
Approx. Protein Concentrations	IgG concentration 0.5 mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	0.5ug/ml	2 ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
Description	Product Code	Applications	Pack Size
Rabbit anti Goat IgG (Fc):FITC	STAR122F	F	100 Tests
Rabbit anti Goat IgG (Fc):HRP	STAR122P	C,E,WB	100 Tests
文献
1.Zhou, W.et al.(2011) Association with endoplasmic reticulum promotes proteasomal degradation of GADD34 protein.J Biol Chem. 286: 21687-96.2.Zhou, W.et al.(2013) Phosphorylation at tyrosine 262 promotes GADD34 protein turnover.J Biol Chem. 288 (46): 33146-55.3.Imbeault, M.et al.(2009) Microarray study reveals that HIV-1 induces rapid type-I interferon-dependent p53 mRNA up-regulation in human primary CD4+ T cells.Retrovirology. 6: 5.

技术参数

产品应用 wb

产品类型 Polyclonal Antibody

推荐用于 wb

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Goat anti Human GADD34 antibody AHP683 bio-rad,Goat anti Human GADD34 antibody

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