Rabbit anti Human interleukin-25 antibody AHP2839Z bio-rad,Rabbit anti Human interleukin-25 antibody

2024-10-22

Rabbit anti Human interleukin-25 antibody

货号:AHP2839Z

规格:0.1 mg

价格:4276

产品类型:免疫组化一抗

品牌:Bio-Rad

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:其它

产品介绍
Rabbit anti Human interleukin-25 antibody,recognizes interleukin-25 (IL-25) also known as IL-17E. IL-25 is a member of the IL-17 family of cytokines and is expressed by various immune cells including mast cells, eosinophils, basophils and T helper type 2 cells. It is also expressed in non-hematopoietic cells such as epithelial and endothelial cells (Yaoet al.2016). As a pleiotropic cytokine, it stimulates stromal, innate immune and adaptive immune cells to regulate Th2 type inflammation (Monin & Gaffen 2018). IL-25 exerts its biological function through its receptor IL-17RB, although there is some evidence that it may also bind to the receptor IL-17RA (Yaoet al.2016). Through this interaction, IL-25 is able to induce expression of IL-4, IL-5, IL-13 and TSLP (McGeachyet al.2019).IL-25 is upregulated in asthmatic conditions and can induce typical eosinophil inflammation and airway hyperresponsiveness (Yaoet al.2016). IL-25 levels are also associated with the severity of chronic allergic reactions (Monin & Gaffen 2018).
产品详情
Target SpeciesHuman
Product FormPurified IgG - lyophilized
ReconstitutionReconstitute with 0.1 ml distilled water
Antiserum PreparationProduced from sera of rabbits immunized with recombinant human interleukin-17E and purified by affinity chromatography
Buffer SolutionPhosphate buffered saline
Preservative StabilisersNone present
ImmunogenE. coliderived recombinant human interleukin-25
Approx. Protein ConcentrationsIgG concentration 1.0 mg/ml after reconstitution
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Prior to reconstitution store at -20°C.After reconstitution store at -20°C.This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting0.1 ug/ml0.2 ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
DescriptionProduct CodeApplicationsPack Size
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技术参数

产品应用 elisa;wb

产品类型 Polyclonal Antibody

推荐用于 elisa;wb

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