Rabbit anti caspase-3 antibody AHP2717 bio-rad,Rabbit anti caspase-3 antibody

2024-10-22

Rabbit anti caspase-3 antibody

货号:AHP2717

规格:50 µl

价格:2576

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:caspase-3

物种:其它

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti caspase-3 antibodyrecognizes caspase-3 also known as cysteine protease CPP32. Caspase-3, as the name implies, is a member of the cysteine-aspartic acid protease (caspase) protein family.Caspase-3 is an effector caspase that is activated by both the intrinsic and extrinsic apoptosis pathways. Caspase-3 is cleaved from an inactive 32 kDa zymogen/pro-enzyme into p17 and p12 subunits by the activated initiator caspases 9 and 8 in apoptotic cells. These subunits dimerize to form the active caspase 3 protein that cleaves and activates caspase-6 and 2. Through the activation/cleavage of downstream caspases, caspase-3 plays an important role in mediating apoptosis signaling.
产品详情
Target SpeciesHuman
Western BlottingRabbit anti caspase-3 antibody detects a band of approximately 32 kDa in Jurkat cell lysate under reducing conditions
Product FormPurified IgG - liquid
Antiserum PreparationAntiserum to caspase-3 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.02% Sodium Azide50% Glycerol
ImmunogenRecombinant human caspase-3
RegulatoryFor research purposes only
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories
Guarantee12 months from date of despatch
存储条件
Store at -20℃Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/5001/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
DescriptionProduct CodeApplicationsPack Size
Goat anti Rabbit IgG (H/L):HRPSTAR124PC,E,WB1mg

Goat anti Rabbit IgG (Fc):BiotinSTAR121BE,WB1mg

技术参数

产品应用 wb

产品类型 Polyclonal Antibody

推荐用于 wb

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