Bio-Rad Catenin Beta抗体 AHP2418,Rabbit anti Catenin Beta

2024-10-22

Rabbit anti Catenin Beta

货号:AHP2418

规格:0.1 mg

价格:3213

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:Catenin Beta

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍

Rabbit anti catenin beta antibodyrecognizes catenin beta, also known as beta-catenin. Catenin beta is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Catenin beta also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.Catenin beta binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in catenin beta are a cause of colorectal cancer, pilomatrixoma (PTR), medulloblastoma (MDB) and ovarian cancer. Three transcript variants encoding the same protein have been found for catenin beta (provided by RefSeq, Oct 2009).

产品详情

Target Species

Human

Species Cross-Reactivity

Target Species Cross Reactivity

Mouse √

Rat √

N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Purified IgG - liquid

Preparation

Purified IgG prepared by affinity chromatography

AntiserumPreparation

Antiserum to catenin beta was raised by repeated immunisation of rabbits with highly purified antigen

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

0.1% Sodium Azide (NaN3)0.2% Gelatin

Immunogen

Peptide mapping to the carboxy terminal of human catenin beta

Approx. Protein Concentrations

IgG concentration 0.2 mg/ml

Regulatory

For research purposes only

Guarantee

12 months from date of despatch

存储条件

Store at +4℃. DO NOT FREEZE.This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

应用

Application Name

Verified

Min Dilution

Max Dilution

Western Blotting

1/400

1/1000

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
  • Western Blotting
  • Rabbit anti catenin beta recognizes a band of approximately 100 kDa when run under reducing conditions

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技术参数

产品应用 WB

产品类型 Polyclonal Antibody

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