Bio-Rad PAK1 (pThr84)抗体 AHP2269,Rabbit anti PAK1 (pThr84)-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad PAK1 (pThr84)抗体 AHP2269,Rabbit anti PAK1 (pThr84)

2024-10-22

Rabbit anti PAK1 (pThr84)

货号：AHP2269

规格：0.1 ml

价格：5287

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：PAK1 (pThr84)

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti PAK1 (pThr84) antibodyrecognizes p21-activated kinases (PAK) 1, also known as serine/threonine-protein kinase PAK 1, alpha-PAK and p65-PAK, when phosphorylated at threonine 84.Serine/threonine-protein kinase PAK1 is an enzyme that in humans is encoded by the PAK1 gene. PAK proteins are critical effectors that link the Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins are a family of serine/threonine p21-activated kinases and include PAK1-6. These proteins serve as targets for small GTP binding proteins such as OSR1.OSR1, oxidative stress response 1, is activated by osmotic stresses including sorbitol or NaCl. It has been predicted that OSR1 phosphorylates PAK1 in the regulatory domain at threonine 84 and inhibits activation of the JNK and MAPK signaling pathway.PAK proteins also serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology.
产品详情
Target Species	Human
Species Cross-Reactivity	Target Species Cross Reactivity
	Bovine Expected from Sequence
	Dog Expected from Sequence
	Chicken Expected from Sequence
	Guinea Pig Expected from Sequence
	Rat Expected from Sequence
	Sheep Expected from Sequence
	Zebrafish Expected from Sequence
	Mouse √
	Primate Expected from Sequence
	N.B. Antibody reactivity and working conditions may vary between species.
Product Form	Purified IgG - liquid
AntiserumPreparation	Antiserum to PAK1 (pThr84) was raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity purification via sequential chromatography on phospho- and dephospho-peptide columns
Buffer Solution	HEPES buffered saline
Preservative Stabilisers	0.09% Sodium Azide (NaN₃)1% Bovine Serum Albumin50% Glycerol
Immunogen	Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr84 (pThr84) region of human PAK1
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√		1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls. Western Blotting Rabbit anti Human PAK1 (pThr84) detects a band at approximately 68 kDa in mouse hippocampal lysate
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技术参数

产品应用 WB

产品类型 Polyclonal Antibody

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Bio-Rad PAK1 (pThr84)抗体 AHP2269,Rabbit anti PAK1 (pThr84)

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