Bio-Rad AHP2074 BIM,Goat anti Human BIM antibody

2024-10-22

Goat anti Human BIM antibody

货号:AHP2074

规格:0.1 mg

价格:4063

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:BIM

物种:人

宿主:山羊

抗体亚型:IgG

荧光染料:Purified

产品介绍
Goat anti Human BIM antibodyrecognizes an epitope within the C-terminal (CT) region of the AD, ACD and ABCD isoforms of human BIM, otherwise known as Bcl-2 interacting mediator of cell death.BIM is an apoptotic activator protein and member of the Bcl-2 family, which forms heterodimers with several anti-apoptotic proteins including BCL2, BHRF1, and MCL1, but not with the pro-apoptotic proteins BAD, BAX or BAK. BIM can be induced by nerve growth factor (NGF) and also by forkhead transcription factor FKHR-L1, implicating BIM in both neuronal and lymphocyte apoptosis.
产品详情

Target Species

Human

Product Form

Purified IgG - liquid

Antiserum Preparation

Antiserum to human BIM (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.

Buffer Solution

TRIS buffered saline

Preservative Stabilisers

0.02% Sodium Azide (NaN3)

0.5% Bovine Serum Albumin

Immunogen

Synthetic peptide sequence C-FNAYYARRLEK from the C-Terminal region of BIM (NP_619528; NP_996886; NP_619529).
Approx. Protein ConcentrationsIgG concentration 0.5 mg/ml

Regulatory

For research purposes only

Guarantee

12 months from date of despatch
存储条件
Prior to reconstitution store at -20°C.After reconstitution store at -20°C.This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用

Application Name

Verified

Min Dilution

Max Dilution

ELISA1/16000
Western Blotting0.52.0ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.Western BlottingAHP2074 detects a band of approximately 23kDa in K562 cell lysates.
数据

Western blot analysis ofK562cell lysate probed with Goat anti human BIM C-Terminal (AHP2074). Detection is by chemiluminescence.
生物信息
Synonyms

Bcl-2 Interacting Mediator Of Cell Death

RRIDAB_2259152
UniProtO43521
Entrez GeneBCL2L11

技术参数

产品应用 E;WB

产品类型 Polyclonal Antibody

推荐用于 E;WB

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