Bio-Rad AHP2065 IFI1 ,Goat anti Human IFI1 antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad AHP2065 IFI1 ,Goat anti Human IFI1 antibody

2024-10-22

Goat anti Human IFI1 antibody

货号：AHP2065

规格：0.1 mg

价格：5083

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原： IFI1

物种：人

宿主：山羊

抗体亚型：IgG

荧光染料：Purified

产品介绍
Goat anti Human IFI1 antibody recognizes human Interferon-induced helicase C domain-containing protein 1, also known as IFIH1, Clinically amyopathic dermatomyositis autoantigen 140 kDa, CADM-140 autoantigen, Helicase with 2 CARD domains, Helicard, Interferon-induced with helicase C domain protein 1, Melanoma differentiation-associated protein 5, MDA-5, Murabutide down-regulated protein, RIG-I-like receptor 2, RLR-2 or RNA helicase-DEAD box protein 116.Variations in the IFIH1 gene affect suceptibility to Insulin dependent diabetes mellitus 19 (IDDM19), a multifactorial disorder of glucose homeostasis with a susceptibility to ketoacidosis (Smyth et al. 2006). Mutations in the IFIH1 gene can lead to the development of Aicardi-Goutieres syndrome 7 (AGS7) a disease characterised by cerebral atrophy, leukoencephalopathy, intracranial calcifications, chronic cerebrospinal fluid (CSF) lymphocytosis, increased CSF alpha-interferon, and negative serologic investigations for common prenatal infection (Oda et al. 2014). Mutations in the IFIH1 gene may also lead to the development of Singleton-Merten syndrome 1 (SGMRT1), a disease featuring aortic calcification, dental abnormalities, osteopenia and acro-osteolysis (Rutsch et al. 2015).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Antiserum Preparation	Antiserum to human IFIH1 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution	TRIS buffered saline
Preservative Stabilisers	0.02% Sodium Azide (NaN3) 0.5% Bovine Serum Albumin
Immunogen	Synthetic peptide sequence SNGYSTDENFRYL-C from the N-Terminal region of IFIH1 (NP_071451.2).
Approx. Protein Concentrations	IgG concentration 0.5 mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Prior to reconstitution store at -20°C.After reconstitution store at -20°C.This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
ELISA	√	1/32000
Immunohistology - Paraffin¹	√	10 ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Tris/EDTA buffer pH 9.0 is recommended for this purpose.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.Histology Positive Control TissueHuman pancreas
数据
Immunohistochemical staining of paraffin embedded human pancreas probed with Goat anti Human IFIH1 antibody (AHP2065) at 10μgml-1following heat mediated antigen retrieval with Tris/EDTA buffer pH9
相关试剂
Description	Product Code	Applications	Pack Size
Antigen Retrieval Buffer, pH8.0	BUF025A	IHC(P)	500 mL

技术参数

产品应用 E;P*

产品类型 Polyclonal Antibody

推荐用于 E;P*

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Bio-Rad AHP2065 IFI1 ,Goat anti Human IFI1 antibody

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