Bio-Rad Transglutaminase 2 抗体 AHP2142,Goat anti Human Transglutaminase 2-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad Transglutaminase 2 抗体 AHP2142,Goat anti Human Transglutaminase 2

2024-10-22

Goat anti Human Transglutaminase 2

货号：AHP2142

规格：0.1 mg

价格：5083

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：Transglutaminase 2

物种：人

宿主：山羊

抗体亚型：IgG

荧光染料：Purified

产品介绍
Goat anti Human transglutaminase 2 antibodyrecognizes human Protein-glutamine gamma-glutamyltransferase 2, also known as Transglutaminase 2 (TGM2), or tissue Transglutaminase (tTG). TGM2 is a 687 amino acid member of the Transglutaminase family. It is a ubiquitously expressed calcium-dependent enzyme, with GTPase activity, which catalyzes protein cross-linking and the conjugation of polyamines to proteins.TGM2 has been implicated in several processes, including apoptosis (Hseihet al.2013), the regulation of cytoskeletal structure, cell-matrix adhesion, cell migration, and wound healing (Fesus and Piacentini 2002). Antibodies against tTG are apparent in a high majority of patients with the autoimmune condition known as celiac disease, resulting in sensitivity to gluten (Geldermanet al.2014). Three isoforms of TGM2 generated by alternative splicing exist. Goat anti Human transglutaminase 2 antibody is generated against a peptide spanning amino acid residues 667-680 of isoform 1. It does not recognize the other isoforms having carboxy-terminal deletions.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
AntiserumPreparation	Antiserum to human TGM2 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution	TRIS buffered saline
Preservative Stabilisers	0.02% Sodium Azide (NaN₃)
Immunogen	Synthetic peptide sequence C-NFESDKLKAVKGFR from the internal region (near the C- Terminal) of TGM2 (NP_004604.2).
Approx. Protein Concentrations	IgG concentration 0.5mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
ELISA	√	1/128000
Western Blotting	√	0.03	0.1ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls. Western Blotting AHP2142 detects a band of approximately 90kDa in human lung cell lysates.
可用二抗
Description	Product Code	Applications	Pack Size
Rabbit anti Goat IgG (Fc):FITC	STAR122F	F	1 mg
Rabbit anti Goat IgG (Fc):HRP	STAR122P	C E WB	1 mg

技术参数

产品应用 E ;WB

产品类型 Polyclonal Antibody

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Bio-Rad Transglutaminase 2 抗体 AHP2142,Goat anti Human Transglutaminase 2

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