Bio-Rad AHP1468 GFAP,Goat anti Human GFAP antibody

2024-10-22

Goat anti Human GFAP antibody

货号:AHP1468

规格:0.1 mg

价格:5083

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:GFAP

物种:人

宿主:山羊

抗体亚型:IgG

荧光染料:Purified

产品介绍
Goat anti Human GFAP antibodyrecognizes an epitope within the C-terminal (CT) region of human GFAP (glial fibrillary acidic protein), a class III intermediate filament (IF) protein specifically expressed by glial cells or cells of glial origin e.g astrocytes, ependymal cells and Schwann cells.GFAP plays a role in several cellular functions within the central nervous system (CNS), including cell structure and stability, communication, motility and mitosis, and is rapidly synthesized during astrogliosis, following trauma/injury. Mutations in the GFAP gene are responsible for the rare autosomal dominant disorder known asAlexander disease, resulting in the destruction of brain white matter and the formation of fibrous, eosinophilic deposits known as Rosenthal fibers. Characteristics of this disease are associated with transgenes and other mutation types in mouse.
产品详情

Target Species

Purified IgG - liquid

Product Form

Purified IgG - liquid

Antiserum Preparation

Antiserum to human GFAP (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.

Buffer Solution

TRIS buffered saline

Preservative Stabilisers

0.02% Sodium Azide (NaN3)0.5% Bovine Serum Albumin

Approx. Protein Concentrations

IgG concentration 0.5mg/ml

Immunogen

Peptide sequence C-DGEVIKESKQEHKD from the C-terminal region of GFAP (NP_002046.1).

Regulatory

For research purposes only

Guarantee

12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用

Application Name

Verified

Min Dilution

Max Dilution

ELISA

1/32000

Western Blotting

1.03.0ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.

Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
  • Western Blotting
  • AHP1468 detects a band of approximately 48kDa in mouse brain cell lysates.
二抗相关产品

Description

Product Code

Applications

Pack Size

Rabbit anti Goat IgG (Fc):FITCSTAR122FFlow1 mg
Rabbit anti Goat IgG (Fc):HRPSTAR122PC;E;WB1 mg
数据

Immunohistochemical staining of paraffin embedded human cerebellum following heat mediated antigen retrieval in citrate buffer pH 6.0 with Goat anti Human GFAP antibody at 2μgml-1followed by secondary anti Goat-HRP and DAB chromogen visualization
文献

1. Gomes, F.C.et al.(1999) Glial fibrillary acidic protein (GFAP): modulation by growth factors and its implication in astrocyte differentiation.Braz J Med Biol Res. 32 (5): 619-31.

技术参数

产品应用 ELISA;WB

产品类型 Polyclonal Antibody

推荐用于 ELISA;WB

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://gibcohyclone.cn/thread-42672.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价