Rabbit anti Rat GSK3 beta (pSer9) antibody AHP1233 bio-rad,Rabbit anti Rat GSK3 beta (pSer9) antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Rat GSK3 beta (pSer9) antibody AHP1233 bio-rad,Rabbit anti Rat GSK3 beta (pSer9) antibody

2024-10-22

Rabbit anti Rat GSK3 beta (pSer9) antibody

货号：AHP1233

规格：0.1 ml

价格：6503

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：GSK3 beta (pSer9)

物种：其它

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Rat GSK3 beta (pSer9) antibodyrecognizes GSK3 beta, also known as glycogen synthase kinase-3 beta (GSK-3 beta), factor A (FA) and serine/threonine-protein kinase GSK3B, when phosphorylated at serine 9. GSK3 is a ~46 kDa member of the serine/threonine protein kinase family. Two isforms of GSK3 exist, alpha and beta. GSK3 beta is expressed in the testis, thymus, prostate, and ovary as well as being expressed at low levels in lung, brain and kidney tissue.GSK3 beta is involved in many signalling pathways including energy metabolism, body pattern formation and microtubule growth and stability (which aids axon growth). GSK3 beta is also thought to be involved in oncogenesis and the hormonal control of several regulatory proteins including glycogen synthase.Phosphorylation of serine-9 inhibits GSK3 beta function.
产品详情
Target Species	Rat
Product Form	Purified IgG conjugated to Biotin - liquid
Antiserum Preparation	Antisera to rat GSK3 beta (pSer9) were raised by repeated immunisations of rabbit with highly purified antigen. Purified IgG prepared by affinity chromatography.
Buffer Solution	10mM Hepes pH7.5
Preservative Stabilisers	0.09%Sodium Azide (NaN3)50%Glycerol0.01%Bovine Serum Albumin
Immunogen	Phosphopeptide corresponding to amino acid sequence surrounding phoshorylated seine 9 of rat GSK3 beta.
Approx. Protein Concentrations	IgG concentration 0.5mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
ELISA	√		1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
Description	Product Code	Applications	Pack Size
Goat anti Rabbit IgG (Fc):Biotin	STAR121B	E,WB	1mg
Goat anti Rabbit IgG (H/L):HRP	STAR124P	C,E,WB	1mg
文献
1.Green, J.B. (2004) Lkb1 and GSK3-beta: kinases at the center and poles of the action.Cell Cycle. 3 (1): 12-4.2.Papkoff, J.et al. (1998) WNT-1 and HGF regulate GSK3 beta activity and beta-catenin signaling in mammary epithelial cells.Biochem. Biophys. Res. Commun. 247:851-8.3.Stambolic, V.et al. (1994) Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation.Biochem, J. 303:701-4.4.Garrido, J.et al. (2007) GSK3 alpha and GSK3 beta are necessary for axon formation.FEBS Lett. 581:1579-86.

技术参数

产品应用 wb

产品类型 Polyclonal Antibody

推荐用于 wb

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Rabbit anti Rat GSK3 beta (pSer9) antibody AHP1233 bio-rad,Rabbit anti Rat GSK3 beta (pSer9) antibody

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