Bio-Rad AHP1421 DAXX,Rabbit anti Human DAXX antibody

2024-10-22

Rabbit anti Human DAXX antibody

货号:AHP1421

规格:50 µg

价格:6095

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:DAXX

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human DAXX antibodyrecognises human Death Domain-Associated Protein 6, a novel Fas binding protein that has been designated DAXX.DAXX binds specifically to the death domain of Fas and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway.DAXX is predominantly a nuclear protein, where it acts as a repressor of EtsI and Pax3 transactivation. When in association with ASK1 kinase DAXX translocates from the nucleus to the cytoplasm.
产品详情

Target Species

Human

Product Form

Purified IgG - liquid

Antiserum Preparation

Antiserum to human DAXX was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

<0.1% Sodium Azide (NaN3)

Approx. Protein Concentrations

IgG concentration 1.0mg/ml

Immunogen

Synthetic peptide corresponding to amino acids 261-274 of human DAXX protein.

Regulatory

For research purposes only

Guarantee

12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用

Application Name

Verified

Min Dilution

Max Dilution

ELISA

1/7000

1/45000

Immunohistology - Paraffin1

2.5ug/ml

Western Blotting

1/2001/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.

1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
  • Histology Positive Control Tissue
  • Human kidney
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数据

Staining of formalin fixed, paraffin embedded human kidney with Rabbit anti Human DAXX (AHP1421).

技术参数

产品应用 ELISA;IHC(P)*;WB

产品类型 Polyclonal Antibody

推荐用于 ELISA;IHC(P)*;WB

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