Bio-Rad AHP1327 VEGF receptor 2,Rabbit anti Human VEGF receptor 2 antibody

2024-10-22

Rabbit anti Human VEGF receptor 2 antibody

货号:AHP1327

规格:50 µg

价格:7310

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:VEGF receptor 2

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human VEGF receptor 2 antibodydetects vascular endothelial growth factor receptor 2 (VEGFR2), a member of the tyrosine kinase family that plays an essential role in transducing the major signals for angiogenesis. VEGFR2 has also been implicated in embryonic development, wound healing, cell proliferation, migration and differentiation.VEGFR2 is expressed mostly on vascular endothelial cells, and is expressed on a subpopulation of haematopoietic cells which might be the progenitor for endothelial cells.Mutated forms of VEGFR2 have been implicated in cancer and diabetic retinopathy, where it results in pathological angiogenesis.
产品详情

Target Species

Human

Product Form

Purified IgG - liquid

Antiserum Preparation

Antisera to human VEGF receptor 2 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

0.1%Sodium Azide (NaN3)

Approx. Protein Concentrations

IgG concentration 0.5 mg/ml

Immunogen

Synthetic peptide corresponding to an internal domain of human VEGF receptor 2, conjugated to Keyhole Limpet Hemocyanin (KLH).

Regulatory

For research purposes only

Guarantee

12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用

Application Name

Verified

Min Dilution

Max Dilution

Immunohistology - Paraffin1

10ug/ml

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.

1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
  • Histology Positive Control Tissue
  • Breast carcinoma.

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Description

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Pack Size

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Goat anti Rabbit IgG (Fc):FITC

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Goat anti Rabbit IgG (Fc):HRP

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Goat anti Rabbit IgG (H/L):HRP

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Sheep anti Rabbit IgG:FITC

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数据
Staining of human breast carcinoma with Rabbit anti Human VEGF Receptor 2 (AHP1327)
文献

1. Shibuya, M. (2006) Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis.J Biochem Mol Biol. 39 (5): 469-78.2. Hjelmgren, O.et al.(2016) Increased Vascularization in the Vulnerable Upstream Regions of Both Early and Advanced Human Carotid Atherosclerosis.PLoS One. 11 (12): e0166918.

技术参数

产品应用 IHC(P)*

产品类型 Polyclonal Antibody

推荐用于 IHC(P)*

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