Bio-Rad AHP1187 TIM-1 ,Rabbit anti TIM-1 antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad AHP1187 TIM-1 ,Rabbit anti TIM-1 antibody

2024-10-22

Rabbit anti TIM-1 antibody

货号：AHP1187

规格：0.1 mg

价格：5440

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：TIM-1

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti TIM-1 antibodydetects T cell immunoglobulin mucin-1 (TIM-1), which was first identified as the receptor used by hepatitis A for viral entry, it is also known as the hepatitis A virus cellular receptor- HAVCR (Curtiss and Colgan 2007), TIM -1 also acts as a receptor for other viruses, including Dengue, Ebola and Marburg (Kondratowiczet al.2011). TIM-1 is a key cell surface protein that binds TIM-4, leading to T cell proliferation and T helper type 2 (Th2) cytokine production.Two splice variants for human TIM-1 exist; TIM-1a is predominantly expressed in the liver, whilst TIM-1b is expressed in the kidney. Expression of TIM-1 in the kidney is thought to be upregulated in damaged tissue, and is thought to assist healing.TIM-1 polymorphisms are associated with susceptibility to allergy and asthma (Mcintireet al.2004).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Antiserum Preparation	Antisera to human TIM-1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.02%Sodium Azide
Approx. Protein Concentrations	IgG concentration 1.0mg/ml
Immunogen	16 amino acid peptide sequence near the centre of human TIM-1.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	1.0	2.0ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage. Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. Western Blotting AHP1187 detects a band of approximately 49kDa in human uterus tissue lysate.
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数据
Western blot analysis of human uterine lysate probed with Rabbit anti Human TIM-1 (AHP1187) at 1(A) and 2(B) ug/ml.
文献
1. Meyers, J.H.et al.(2005) The TIM gene family regulates autoimmune and allergic diseases.Trends Mol Med. 11 (8): 362-9.2. Hein, R.M. & Woods, M.L. (2007) TIM-1 regulates macrophage cytokine production and B7 family member expression.Immunol Lett. 108 (1): 103-8.

技术参数

产品应用 WB

产品类型 Polyclonal Antibody

推荐用于 WB

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Bio-Rad AHP1187 TIM-1 ,Rabbit anti TIM-1 antibody

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