Bio-Rad AHP1182 XEDAR,Rabbit anti Human XEDAR antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad AHP1182 XEDAR,Rabbit anti Human XEDAR antibody

2024-10-22

Rabbit anti Human XEDAR antibody

货号：AHP1182

规格：0.1 mg

价格：2865

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原： XEDAR

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human XEDAR antibodydetects human X-linked ectodermal dysplasia receptor (XEDAR), a ~33 kDa type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily. XEDAR is a homologue of the ectodermal dysplasia receptor (EDAR), and binds to an isoform of ectodysplasin termed EDA-A2. Binding of ectodysplasin to XEDAR results in the induction of apoptosis, and is thought to be involved ectodermal organ development. XEDAR may also be involved in skeletal muscle development.Two predominant isoforms of XEDAR exist; XEDAR-s and XEDAR-L, produced by alternative splicing.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Antiserum Preparation	Antisera to XEDAR were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.02%Sodium Azide
Approx. Protein Concentrations	IgG concentration 1.0mg/ml
Immunogen	Recombinant human XEDAR.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	0.5	2.0ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage. Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. Western Blotting AHP1182 detects a band of approximately 33kDa in 293 cell lysates.
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文献
1. Sinha, S.K.et al.(2002) Role of TRAF3 and -6 in the activation of the NF-kappa B and JNK pathways by X-linked ectodermal dysplasia receptor.J Biol Chem. 277 (47): 44953-61.2. Sinha, S.K. & Chaudhary, P.M. (2004) Induction of apoptosis by X-linked ectodermal dysplasia receptor via a caspase 8-dependent mechanism.J Biol Chem. 279 (40): 41873-81.3. Newton, K.et al.(2004) Myodegeneration in EDA-A2 transgenic mice is prevented by XEDAR deficiency.Mol Cell Biol. 24 (4): 1608-13.

技术参数

产品应用 WB

产品类型 Polyclonal Antibody

推荐用于 WB

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Bio-Rad AHP1182 XEDAR,Rabbit anti Human XEDAR antibody

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