Bio-Rad AHP1181 CD281 ,Rabbit anti Human CD281 antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bio-Rad AHP1181 CD281 ,Rabbit anti Human CD281 antibody

2024-10-22

Rabbit anti Human CD281 antibody

货号：AHP1181

规格：0.1 mg

价格：2933

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：CD281

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human CD281 antibodydetects an epitope within the N-terminal (NT) region of CD281, also known as toll like receptor 1 (TLR1). TLRs recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and serve as an important link between the innate and adaptive immune response through the production of cytokines. TLR1 is co-expressed with TLR2 on monocytes and dendritic cells where they form heterodimers that can recognize peptidoglycan and bacterial lipopeptides, and in particular triacylated lipoproteins.TLR1 can also regulate other TLR responses; TLR1 can associate with TLR4 and inhibit its signalling in endothelial cells, and can associate with TLR2 to inhibit the TLR2/TLR6 mediated response to phenol-soluble modulin.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Antiserum Preparation	Antisera to CD281 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.02%Sodium Azide (NaN₃)
Approx. Protein Concentrations	IgG concentration 1.0mg/ml
Immunogen	A 16 amino acid peptide located near the amino terminus of human CD281.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Immunohistology - Frozen	√		10ug/ml
Western Blotting	√	1	4ug/ml
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls. Histology Positive Control Tissue Mouse spleen. Western Blotting Rabbit anti Human CD281 detects a band of approximately 90kDa in mouse spleen lysates.
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Description	Product Code	Applications	Pack Size
Goat anti Rabbit IgG (Fc):Biotin	STAR121B	E;WB	1 mg
Goat anti Rabbit IgG (Fc):FITC	STAR121F	Flow	1 mg
Goat anti Rabbit IgG (Fc):HRP	STAR121P	E;WB	1 mg
Goat anti Rabbit IgG (H/L):HRP	STAR124P	C;E;WB	1 mg
Sheep anti Rabbit IgG:FITC	STAR34B	C;F	1 mg
数据
Western blot analysis of mouse spleen lysate probed with Rabbit anti Human CD281 (AHP1181) at 1(A), 2(B) and 4(C) ug/ml.
文献
1. Hajjar, A.M .et al.(2001) Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin.J Immunol. 166 (1): 15-9.2. Janssens, S. & Beyaert, R. (2003) Role of Toll-like receptors in pathogen recognition.Clin Microbiol Rev. 16 (4): 637-46.3. Spitzer JHet al.(2002) Toll-like receptor 1 inhibits Toll-like receptor 4 signaling in endothelial cells.Eur J Immunol. 32 (4): 1182-7.

技术参数

产品应用 IHC(F);WB

产品类型 Polyclonal Antibody

推荐用于 IHC(F);WB

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Bio-Rad AHP1181 CD281 ,Rabbit anti Human CD281 antibody

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