Bio-Rad AHP1180T IRF7,Rabbit anti IRF7 antibody

2024-10-22

Rabbit anti IRF7 antibody

货号:AHP1180T,AHP1180

规格:50 µg,0.1 mg

价格:2763,5372

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:IRF7

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti IRF7 antibodydetects an epitope within the C-terminal (CT) of human interferon regulatory factor 7 (IRF7), a ~54 kDa transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production.Multiple IRF7 transcript variants have been identified.
产品详情

Target Species

Human

Product Form

Purified IgG - liquid

Antiserum Preparation

Antisera to human IRF7 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

Pack Size: 0.1 mg

Pack Size: 50 µg

<0.1% Sodium Azide (NaN3)

Approx. Protein Concentrations

IgG concentration 1.0mg/ml

Immunogen

14 amino acid peptide sequence near the carboxy terminus of human IRF7.

Regulatory

For research purposes only

Guarantee

12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用

Application Name

Verified

Min Dilution

Max Dilution

Western Blotting

0.5Pack Size: 0.1 mg1.0Pack Size: 50 µg

1.0ug/mlPack Size: 0.1 mg2.0ug/mlPack Size: 50 µg

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.

Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
  • Western Blotting
  • AHP1180 detects a band of approximately 51kDa in 293 whole cell lysate.
二抗相关产品

Description

Product Code

Applications

Pack Size

Goat anti Rabbit IgG (Fc):Biotin

STAR121B

E;WB

1 mg

Goat anti Rabbit IgG (Fc):FITC

STAR121F

Flow

1 mg

Goat anti Rabbit IgG (Fc):HRP

STAR121P

E;WB

1 mg

Goat anti Rabbit IgG (H/L):HRP

STAR124P

C;E;WB

1 mg

Sheep anti Rabbit IgG:FITC

STAR34B

C;F

1 mg

数据
Immunohistochemical staining of mouse spleen with Rabbit anti Human IRF7 (AHP1180)
文献

References for IRF7 antibody1. Rautela, J.et al.(2015) Loss of Host Type-I IFN Signaling Accelerates Metastasis and Impairs NK-cell Antitumor Function in Multiple Models of Breast Cancer.Cancer Immunol Res. 3 (11): 1207-17.2. Saitoh, S.I.et al.(2017) TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells.Nat Commun. 8 (1): 1592.Further Reading1. Ning, S.et al.(2005) Regulation of the transcriptional activity of the IRF7 promoter by a pathway independent of interferon signaling.J Biol Chem. 280 (13): 12262-70.2. Prakash, A. & Levy, D.E. (2006) Regulation of IRF7 through cell type-specific protein stability.Biochem Biophys Res Commun. 342 (1): 50-6.

技术参数

产品应用 WB

产品类型 Polyclonal Antibody

推荐用于 WB

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://gibcohyclone.cn/thread-42758.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价