| 产品介绍 | | |
| Rat anti Human Somatostatin antibody, clone YC7recognizes somatostatin, a hormone involved in endocrine system regulation through interactions with pituitary growth hormone, thyroid stimulating hormone, and a number of hormones of the gastrointestinal tract. Somatostatin has active 14 amino acid and 28 amino acid forms, produced by alternate cleavage of the gene product.This antibody does not cross react with enkephalins, other endorphins, substance P, or CGRP. It partially cross reacts with somatostatin fragments.The epitope recognized by this antibody lies within the 1-14 amino acid sequence of cyclic somatostatin. |
| 产品详情 | | |
Target Species | Human |
Product Form | Tissue Culture Supernatant - liquid |
Fusion Partners | Spleen cells from rats immunised with somatostatin conjugated to thyroglobulin were fused with a rat myeloma cell line. |
Preservative Stabilisers | 0.05% Thiomersal |
Immunogen | Somatostatin conjugated to thyroglobulin. |
Regulatory | For research purposes only |
Guarantee | 12 months from date of despatch |
| 存储条件 | | |
| This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. |
| 应用 | | |
Application Name | Verified | Min Dilution | Max Dilution |
Immunohistology - Paraffin | √ | | |
Immunohistology - Frozen | √ | | |
| This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls. |
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| 数据 |
| Published customer image:Rat anti Human Somatostatin antibody, clone YC7 (8330-0009) used to detect neuronal tissue in Zebrafish tissues by immunofluorescence.Image caption:Section from the adult pancreas stained with antibody against galanin (a–c) and Hu (b), and somatostatin (c). RFP marked mnx1+ population of β cells in the transgenic line of the zebrafish (a–c). RFP+ cells were present mostly only in one (primary) islet, whereas somatostatin-positive cells were located in all the islets (a–c). Ganglion containing galanin-IR neurons is visible outside the pancreatic tissue, close to the intestinal wall (a, a″', c, c'). Neurons inside the pancreatic tissue are also visible; however, they were mostly galanin-negative (arrowheads, b). Galanin-IR fibers richly supplied pancreatic islets (c).Iintestine,Pipancreatic islet. Scale bars 100 μmFrom: Podlasz P, Jakimiuk A, Chmielewska-Krzesinska M, Kasica N, Nowik N, Kaleczyc J.Galanin regulates blood glucose level in the zebrafish: a morphological and functional study.Histochem Cell Biol. 2016 Jan;145(1):105-17. |
| 文献 |
| 1. Pidsudko, Z.et al. (2004) Distribution and chemical coding of neurons in intramural ganglia of the porcine urinary bladder trigone.Folia Histochem Cytobiol. 42: 3-11.2. Van Nassauw, L.et al.(2002) Neurochemical identification of enteric neurons expressing P2X(3) receptors in the guinea-pig ileum.Histochem Cell Biol. 118 (3): 193-203.3. Geuens, E.et al. (2003) A globin in the nucleus!J Biol Chem. 278: 30417-20.4. Kaleczyc, J.et al. (2002) Distribution, immunohistochemical characteristics and nerve pathways of primary sensory neurons supplying the porcine vas deferens.Cell Tissue Res. 310: 9-17.5. Pidsudko, Z. (2014) Immunohistochemical characteristics and distribution of sensory dorsal root Ganglia neurons supplying the urinary bladder in the male pig.J Mol Neurosci. 52 (1): 71-81.6. Hens, J.et al.(2001) Morphological and neurochemical identification of enteric neurones with mucosal projections in the human small intestine.J Neurochem. 76: 464-71. |
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