Recombinant Human IL-1α
货号：200-01A-10,200-01A-100,200-01A-1000,200-01A-2,200-01A-250,200-01A-50,200-01A-500
规格：10ug,100ug,1mg,2ug,250ug,50ug,500ug
价格：1418,8297,33241,582,14522,4977,21570
产品类型：细胞因子添加物
品牌：PeproTech
| 产品描述：IL-1α is a non-secreted, proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1α and IL-1β bind to the same receptor and have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B cell maturation and proliferation, mitogenic FGF-like activity and the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant Human IL-1α is an 18.0 kDa protein containing 159 amino acid residues.来源:E.coli别名:Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)氨基酸序列:SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA纯度:≥ 98% by SDS-PAGE gel and HPLC analyses.生物活性:TheED50as determined by the dose-dependent stimulation of murine D10S cells is ≤ 0.001 ng/ml, corresponding to a specific activity of ≥ 1 x 109units/mg.Calculated Molecular Weight:18 kDaAccession Number:P01583Gene ID:3552交叉反应:Cow,Frog,Human,Monkey,Mouse,Pig原产国:USA |
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