PeproTech 200-39 重组人IL-37 (IL-1F7) ,Recombinant Human IL-37 (IL-1F7)-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

PeproTech 200-39 重组人IL-37 (IL-1F7) ,Recombinant Human IL-37 (IL-1F7)

2024-10-23

Recombinant Human IL-37 (IL-1F7)

货号：200-39-100,200-39-1000,200-39-25,200-39-250,200-39-5,200-39-500

规格：100ug,1mg,25ug,250ug,5ug,500ug

价格：6410,25699,1425,11216,585,16669

产品类型：细胞因子添加物

品牌：PeproTech

产品描述：The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-37 (IL-1F7), which acts as a modulator of the immune response. Reduction of IL-37 synthesis in PBMCs leads to increased production of proinflammatory cytokines including IL-1 alpha, IL-1 beta, IL-6 and TNF- alpha. The role of IL-37 as an inhibitor of the innate inflammatory response is also corroborated by the observation that it is highly expressed in synovial tissue from patients with rheumatoid arthritis. Full length IL-37 resides primarily in the cytoplasm, but after activation through cleavage by CASP1, it can translocate to the nucleus where it exerts its activity by direct interaction with SMAD3. Recombinant Human IL-37 is a 19.4 kDa protein consisting of 174 amino acids, corresponding to the mature activated form of IL-37.来源:E.coli别名:Interleukin-37, IL-1F7, IL-1ζ (zeta), IL-1H4氨基酸序列:MVHTSPKVKN LNPKKFSIHD QDHKVLVLDS GNLIAVPDKN YIRPEIFFAL ASSLSSASAE KGSPILLGVS KGEFCLYCDK DKGQSHPSLQ LKKEKLMKLA AQKESARRPF IFYRAQVGSW NMLESAAHPG WFICTSCNCN EPVGVTDKFE NRKHIEFSFQ PVCKAEMSPS EVSD纯度:≥ 95% by SDS-PAGE gel and HPLC analyses.生物活性:Measured by its ability to bind Interleukin-18 Binding Protein isoform a (IL-18 BPa) in functional ELISA.Calculated Molecular Weight:19.4 kDaAccession Number:Q9NZH6Gene ID:27178交叉反应:Human原产地:USA仅用于科研，不能用于临床和诊断。

技术参数

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PeproTech 200-39 重组人IL-37 (IL-1F7) ,Recombinant Human IL-37 (IL-1F7)

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