Recombinant Human IL-37 (IL-1F7)
货号:200-39-100,200-39-1000,200-39-25,200-39-250,200-39-5,200-39-500
规格:100ug,1mg,25ug,250ug,5ug,500ug
价格:6410,25699,1425,11216,585,16669
产品类型:细胞因子添加物
品牌:PeproTech
产品描述:The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-37 (IL-1F7), which acts as a modulator of the immune response. Reduction of IL-37 synthesis in PBMCs leads to increased production of proinflammatory cytokines including IL-1 alpha, IL-1 beta, IL-6 and TNF- alpha. The role of IL-37 as an inhibitor of the innate inflammatory response is also corroborated by the observation that it is highly expressed in synovial tissue from patients with rheumatoid arthritis. Full length IL-37 resides primarily in the cytoplasm, but after activation through cleavage by CASP1, it can translocate to the nucleus where it exerts its activity by direct interaction with SMAD3. Recombinant Human IL-37 is a 19.4 kDa protein consisting of 174 amino acids, corresponding to the mature activated form of IL-37.来源:E.coli别名:Interleukin-37, IL-1F7, IL-1ζ (zeta), IL-1H4氨基酸序列:MVHTSPKVKN LNPKKFSIHD QDHKVLVLDS GNLIAVPDKN YIRPEIFFAL ASSLSSASAE KGSPILLGVS KGEFCLYCDK DKGQSHPSLQ LKKEKLMKLA AQKESARRPF IFYRAQVGSW NMLESAAHPG WFICTSCNCN EPVGVTDKFE NRKHIEFSFQ PVCKAEMSPS EVSD纯度:≥ 95% by SDS-PAGE gel and HPLC analyses.生物活性:Measured by its ability to bind Interleukin-18 Binding Protein isoform a (IL-18 BPa) in functional ELISA.Calculated Molecular Weight:19.4 kDaAccession Number:Q9NZH6Gene ID:27178交叉反应:Human原产地:USA仅用于科研,不能用于临床和诊断。 |
©
bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:
https://gibcohyclone.cn/thread-43858.htm
特别声明:以上内容(如有图片亦包括在内)来源于授权厂家或网络,如有侵权,请联系删除,本平台不提供信息存储服务。
Notice: The content above (including the pictures if any)comes from authorized manufacturers or networks. In case of infringement, please contact to delete it. This platform does not provide information storage services.