Cytokeratin 14 Polyclonal Antibody

货号：PA5-16722

规格：500 µL

价格：4880

产品类型：抗体和染料

品牌：Thermo Fisher

物种：人/小鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	单抗	同型对照：
浓度：		用法：	1 µg/mL (WB)；1:200(IHC (P))

产品详细信息PA5-16722 targets Cytokeratin 14 in immunohistochemistry (paraffin and Western blot applications and shows reactivity with Human samples.The PA5-16722 immunogen is a synthetic peptide derived from C-terminal of human Keratin 14.靶标信息Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.

数据

Cytokeratin 14 Antibody (PA5-16722) in IHCFormalin-fixed, paraffin-embedded human squamous cell carcinoma stained with Keratin 14 antibody using peroxidase-conjugate and AEC. Note cytoplasmic staining of tumor cells

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