TCF2 Polyclonal Antibody

货号：PA124459

规格：50 µg

价格：5901

产品类型：抗体和染料

品牌：Thermo Fisher

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	多抗	同型对照：
浓度：	0.5 mg/mL	用法：	0.2-2.5 µg/mL(WB)

产品详细信息Recommended positive controls: Jurkat.Predicted reactivity: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%.Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.靶标信息Hepatocyte Nuclear Factor 1 (HNF1, Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor) is a member of the homeodomain-containing superfamily of transcription factors. It is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. HNF1has been shown to function in nephron development and regulates development of the embryonic pancreas. Mutations in the gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of the gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

数据

TCF2 Antibody (PA1-24459) in WBWestern Blot analysis of TCF2 was performed by loading Jurkat cells. Proteins were transferred to a membrane and probed with a TCF2 Polyclonal Antibody (Product # PA1-24459) at a dilution of 0.2-1 µg/mL.

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技术参数

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