Cytokeratin 14 Polyclonal Antibody/KRT14多抗

货号：PA5-28002

规格：100 µL

价格：5438

产品类型：免疫组化一抗

品牌：Thermo Fisher

抗原：Recombinant fragment corresponding to a region wit

物种：人/小鼠/大鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	多抗	同型对照：	IgG
浓度：	0.48 mg/mL	用法：	1:100-1:1000(ICC);1:100-1:1000(IF);1:100-1:1000(IHC(P));1:100-1:1000(IHC(F));1:1000-1:10000(WB)

产品详细信息Recommended positive controls: HeLa , * rat olfactory epithelium.Predicted reactivity: Mouse (95%), Rat (94%), Dog (96%), Bovine (96%).Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.靶标信息Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (ie. skin) and non-keratinizing cells (ie. mesothelial cells). At least 20 different CKs can be identified. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). Belonging to the type I subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells.仅用于科研。不用于诊断过程。未经明确授权不得转售。

数据

Cytokeratin 14 Antibody (PA5-28002) in WBWestern blot analysis of Cytokeratin 14 using A) 30 µg Neuro2A whole cell lysate (B) 30 µg GL261 whole cell lysate and C) 30 µg C8D30 whole cell lysate. Samples were loaded onto a 10% SDS-PAGE gel and probed with a Cytokeratin 14 polyclonal antibody (Product # PA5-28002) at a dilution of 1:500. Cytokeratin 14 Antibody (PA5-28002) in IFImmunofluorescent analysis of Cytokeratin 14 in paraformaldehyde-fixed HeLa cells using a Cytokeratin 14 polyclonal antibody (Product # PA5-28002) at a 1:200 dilution. Cytokeratin 14 Antibody (PA5-28002) in IHC (P)Immunohistochemical analysis of Cytokeratin 14 in paraffin-embedded lung carcinoma using a Cytokeratin 14 polyclonal antibody (Product # PA5-28002) at a dilution of 1:100.

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参考文献：

1.Journal of the American Academy of DermatologyHuman polyomavirus 6 and 7 are associated with pruritic and dyskeratotic dermatoses.

技术参数

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