IL-2 Monoclonal Antibody (JES6-5H4), eBioscience/IL-2单克隆抗体（JES6-5H4）

货号：BMS180

规格：100 µg

价格：2806

产品类型：流式抗体

品牌：eBioscience

物种：小鼠

宿主：大鼠

抗体亚型：其它

克隆号：JES6-5H4

荧光染料：其它

类型:	单抗	同型对照：
浓度：	0.5 mg/mL	用法：	Assay-Dependent（ELISA)；Assay-Dependent(IP)；Assay-Dependent(IHC)；Assay-Dependent（Flow）；Assay-Dependent（WB）

产品详细信息Description: BMS180 (JES6-5H4) is raised against recombinant full length IL-2 of mouse origin and recommended for detection of recombinant and native IL-2 of mouse origin by IP,ELISA, FC, WB. The antibody was purified from tissue culture supernatant by protein G column chromatography.Applications Tested: ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blotting.靶标信息Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.

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流式抗体

参考文献：

1. OncoimmunologyTasquinimod modulates tumor-infiltrating myeloid cells and improves the antitumor immune response to PD-L1 blockade in bladder cancer.2. Nature communicationsC1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation.3. The Journal of clinical investigationTIGIT predominantly regulates the immune response via regulatory T cells.4. Journal of immunology (Baltimore, Md. : 1950)Polyinosinic-polycytidylic acid treatment of Friend retrovirus-infected mice improves functional properties of virus-specific T cells and prevents virus-induced disease.

技术参数

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