Human IL-13 Recombinant Protein, eBioscience/人IL-13重组蛋白

货号：BMS351

规格：10 µg

价格：5591

产品类型：蛋白表达研究

品牌：eBioscience

产品详细信息Description: Interleukin-13 is an immunoregulatory protein produced by activated T-lymphocytes. The biological activities of IL-13 include the stimulation of B cell proliferation and immunoglobulins production. Recombinant human IL-13 is a 12.5 kDa protein containing 114 amino acid residues.Purity: >95%.Molecular Weight: 12.5 kDa.靶标信息IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.

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