Human Dnmt3b ELISA Kit ELISA试剂盒,Human Dnmt3b ELISA Kit/人Dnmt3b ELISA试剂盒

2024-10-23

Human Dnmt3b ELISA Kit/人Dnmt3b ELISA试剂盒

货号:EH158RB,EH158RBX5,EH158RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.64 ng/mL

检测范围0.64-150 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameDNMT3B
Protein aliasesDNA (cytosine-5)-methyltransferase 3B, DNA (cytosine-5-)-methyltransferase 3 beta, DNA methyltransferase HsaIIIB, DNA MTase HsaIIIB, Dnmt3b

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesDNMT3B, ICF, ICF1, M.HsaIIIB
Gene ID(Human) 1789
Gene symbolDNMT3B
UniProt ID(Human) Q9UBC3
Human Dnmt3b quantitates human Dnmt3b in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Dnmt3b.人Dnmt3b定量检测血清,血浆,上清液中的人Dnmt3b。 该检测试剂盒将专门识别天然和重组人Dnmt3b。Target information 靶标信息CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Six alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.CpG甲基化是一种表观遗传修饰,对胚胎发育,印迹和X染色体失活很重要。 小鼠研究表明,哺乳动物的发育需要DNA甲基化。 该基因编码DNA甲基转移酶,其被认为在从头甲基化而不是维持甲基化中起作用。 该蛋白质主要定位于细胞核,其表达受到发育调节。 此基因的突变会导致免疫缺陷中心蛋白不稳定面部异常(ICF)综合征。 已经描述了六个选择性剪接的转录物变体。 变体4和5的全长序列尚未确定。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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