Human LAMP2/CD107b ELISA Kit ELISA试剂盒,Human LAMP2/CD107b ELISA Kit/人LAMP2 / CD107b ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human LAMP2/CD107b ELISA Kit ELISA试剂盒,Human LAMP2/CD107b ELISA Kit/人LAMP2 / CD107b ELISA试剂盒

2024-10-23

Human LAMP2/CD107b ELISA Kit/人LAMP2 / CD107b ELISA试剂盒

货号：EH295RB,EH295RBX5,EH295RBX10

规格：96 tests,5X96 tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.3 ng/mL
检测范围	0.307-75 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	LAMP2 (CD107b)
Protein aliases	CD107 antigen-like family member B, CD107b, LAMP-2, LGP-96, lysosomal-associated membrane protein 2, Lysosome-associated membrane glycoprotein 2
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	CD107b, LAMP-2, LAMP2, LAMPB, LGP110
Gene ID	(Human) 3920
Gene symbol	LAMP2
UniProt ID	(Human) P13473

Human LAMP2/CD107b quantitates human LAMP2/CD107b in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human LAMP2/CD107b.人LAMP2 / CD107b定量检测血清，血浆，上清液中的人LAMP2 / CD107b。该检测试剂盒将专门识别天然和重组人LAMP2 / CD107b。Target information 靶标信息LAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins. LAMP2 provides selectins with carbohydrate ligands, and may play a role in tumor cell metastasis, and have a function in the protection, maintenance, and adhesion of the lysosome. Prior to posttranslational modification, LAMP2 is approximately 46 kDa polypeptide. Mature, functional LAMP2 is extensively glycosylated with a variety of different N-linked and O-linked oligosaccharides with a total molecular weight of about 100-130 kDa. LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail. LAMP2 is used to monitor a very selective form of autophagy called chaperone-mediated autophagy. LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail. The LAMP protein has 3 variant forms: LAMP-2A, -2B, and 2C. LAMP2, together with CD107a/LAMP-1, is a major constituent of lysosomal membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes, and LAMP2 is an important regulator in successful phagosomal maturation. LAMP2 deficiency causes an accumulation of autophagosomes in many tissues leading to cardiomyopathy and myopathy (Danon’s disease).LAMP2（与脂质体相关的膜糖蛋白2，CD107b）是膜糖蛋白家族的成员。 LAMP2为选择素提供碳水化合物配体，并可能在肿瘤细胞转移中发挥作用，并在溶酶体的保护，维持和粘附中起作用。在翻译后修饰之前，LAMP2为约46kDa的多肽。成熟的功能性LAMP2被各种总分子量约为100-130 kDa的不同N-连接和O-连接的寡糖广泛糖基化。 LAMP 2具有由大的氨基末端溶酶体内部结构域，疏水的跨膜结构域和短的羧基末端细胞质尾部组成的结构。 LAMP2用于监视非常自选的自噬形式，称为伴侣介导的自噬。 LAMP 2具有由大的氨基末端溶酶体内部结构域，疏水的跨膜结构域和短的羧基末端细胞质尾部组成的结构。 LAMP蛋白具有3种变异形式：LAMP-2A，-2B和2C。 LAMP2与CD107a / LAMP-1一起是溶酶体膜的主要成分。 LAMP蛋白参与溶酶体的生物发生，是溶酶体与吞噬体融合的必需条件，而LAMP2是成功吞噬体成熟的重要调控因子。 LAMP2缺乏会导致许多组织中自噬体的积累，从而导致心肌病和肌病（达农病）。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Human LAMP2/CD107b ELISA Kit ELISA试剂盒,Human LAMP2/CD107b ELISA Kit/人LAMP2 / CD107b ELISA试剂盒

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