Human MD-2 ELISA Kit ELISA试剂盒,Human MD-2 ELISA Kit/人MD-2 ELISA试剂盒

2024-10-24

Human MD-2 ELISA Kit/人MD-2 ELISA试剂盒

货号:EH318RB,EH318RBX5,EH318RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

1.6 ng/mL

检测范围1.6-400 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameMD-2
Protein aliasesESOP-1, Ly-96, Lymphocyte antigen 96, myeloid differentiation protein-2, Protein MD-2

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesESOP-1, ESOP1, ly-96, LY96, MD-2, MD2
Gene ID(Human) 23643
Gene symbolLY96
UniProt ID(Human) Q9Y6Y9
Human MD-2 quantitates human MD-2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human MD-2.人MD-2定量测定血清,血浆,上清液中的人MD-2。 该检测试剂盒将专门识别天然和重组人MD-2。Target information 靶标信息Toll-like receptors (TLRs) are evolutionarily conserved patternrecognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD -1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.Toll样受体(TLR)是进化上保守的模式识别分子,可在感染过程中识别不同的微生物产物,并充当先天性和适应性免疫反应之间的重要纽带。 这些TLR的信号传导通过内源性抑制蛋白(如RP105)的表达受到严格控制,RP105是最近发现的TLR4同源物。 该蛋白与MD-1结合,与TLR4 / MD-2信号通路相互作用并抑制TLR4 / MD-2信号通路。 虽然MD-2可以直接结合LPS(TLR4的激活分子之一),但MD -1的功能鲜为人知。 然而,已经提出,RP105 / MD-1复合物影响由TLR4 / MD-2和TLR2受体复合物介导的抗体产生。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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