Human PON1 ELISA Kit ELISA试剂盒,Human PON1 ELISA Kit/人PON1 ELISA试剂盒

2024-10-24

Human PON1 ELISA Kit/人PON1 ELISA试剂盒

货号:EH376RB,EH376RBX5,EH376RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.2 ng/mL

检测范围0.2-50 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein namePON1
Protein aliasesA-esterase 1, Aromatic esterase 1, arylesterase 1, arylesterase B-type, esterase A, K-45, paraoxonase B-type, PON 1, serum aryldiakylphosphatase, Serum aryldialkylphosphatase 1, Serum paraoxonase/arylesterase 1

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesESA, MVCD5, PON, PON1
Gene ID(Human) 5444
Gene symbolPON1
UniProt ID(Human) P27169
Human PON1 quantitates human PON1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human PON1.人PON1定量检测血清,血浆,上清液中的人PON1。 该检测试剂盒将专门识别天然和重组人PON1。Target information 靶标信息The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson's disease.人的对氧磷酶(PON)基因家族有3个成员,PON1,PON2和PON3,在染色体7q21.3-22.1的长臂上彼此相邻排列。 其中的PON1主要在肝脏中合成,一部分分泌到血浆中,与高密度脂蛋白(HDL)相关。 并水解其他几种有机磷杀虫剂(例如毒死,重氮x)以及神经毒剂(如沙林,梭曼和VX(致命神经毒剂))的活性代谢物。 PON1基因多态性可能与神经变性有关,并被认为是帕金森氏病的独立危险因素。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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