Phospho-PKC beta (Thr641) Polyclonal Antibody

货号：PA5-37692

规格：100 µL

价格：4805

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Peptide sequence around phosphorylation site of th

物种：人/小鼠/大鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	1 mg/mL	用法：	1:100-1:200(ICC);1:100-1:200(IF);1:50-1:100(IHC(P));1:500-1:1000(WB)

产品详细信息A suggested positive control for Western blot is JK cells; suggested positive control for IHC is human lung carcinoma; suggested positive control for ICC/IF is MCF-7 cells. 靶标信息Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

数据：

Phospho-PKC beta (Thr641) Antibody (PA5-37692) in IF Immunofluorescence staining of methanol-fixed MCF-7 cells using PKCbeta (pThr641) polyclonal antibody (Product # PA5-37692) (red). Phospho-PKC beta (Thr641) Antibody (PA5-37692) in IHC (P) Immunohistochemical analysis of paraffin-embedded human lung carcinoma using PKCbeta (pThr641) polyclonal antibody (Product # PA5-37692). Phospho-PKC beta (Thr641) Antibody (PA5-37692) in WBWestern blot analysis of extracts from JK cells, untreated or treated with PMA, using PKCbeta (pThr641) polyclonal antibody (Product # PA5-37692).

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