PRMT5 Polyclonal Antibody

货号：PA5-90290

规格：100 µL

价格：4732

产品类型：标签抗体

品牌：Thermo Fisher

抗原：A synthetic peptide corresponding to a sequence wi

物种：人/小鼠/大鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	3.83 mg/mL	用法：	1:50-1:200(ICC);1:50-1:200(IF)；1:50-1:100（IHC(P)）;1:500-1:2000(WB)

产品详细信息Positive Samples: Jurkat, HepG2, HeLa, NIH/3T3, PC-12, COS-1; Cellular Location: Cytoplasm, Golgi apparatus, Nucleus 靶标信息PRMT5 (protein arginine N-methyltransferase 5) is an arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. PRMT5 specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 and Sm D3; such methylation is required for the assembly and biogenesis of snRNP core particles.

数据：

PRMT5 Antibody (PA5-90290) in ICC Immunocytochemistry-Immunofluorescence analysis of PRMT5 was performed in U2OS cells using PRMT5 Polyclonal Antibody (Product # PA5-90290). PRMT5 Antibody (PA5-90290) in IHCImmunohistochemistry analysis of PRMT5 in paraffin-embedded mouse brain using PRMT5 Polyclonal Antibody (Product # PA5-90290) at a dilution of 1:100. PRMT5 Antibody (PA5-90290) in WB Western Blot analysis of PRMT5 in extracts of various cell lines using PRMT5 Polyclonal Antibody (Product # PA5-90290) at a dilution of 1:1000. A HRP Goat Anti-Rabbit IgG (H+L) secondary antibody was used at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.

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