Human FCGR3A/CD16A ELISA Kit ELISA试剂盒,Human FCGR3A/CD16A ELISA Kit/人FCGR3A / CD16A ELISA试剂盒

2024-10-24

Human FCGR3A/CD16A ELISA Kit/人FCGR3A / CD16A ELISA试剂盒

货号:EH181RB,EH181RBX5,EH181RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

1.35 ng/mL

检测范围1.311-320 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCD16
Protein aliasesCD16a, CD16a antigen, CD16b, Fc fragment of IgG low affinity IIIa receptor, Fc fragment of IgG, low affinity III, receptor for (CD16), low affinity IIIa, receptor (CD16a), low affinity IIIb, receptor (CD16b), Fc gamma receptor III-A, Fc gamma receptor IIIa, Fc gamma receptor IIIb, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIII-beta, Fc-gamma RIIIa, fc-gamma RIIIb, FcgammaRIIIA, FcR-10, IgG Fc receptor III-1, IgG Fc receptor III-2, immunoglobulin G Fc receptor III, Low affinity immunoglobulin gamma Fc region receptor III-A, Low affinity immunoglobulin gamma Fc region receptor III-B, neutrophil-specific antigen NA

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCD16, CD16A, CD16B, FCG3, FCGR3, FCGR3A, FCGR3B, FCGRIII, FCR-10, FCRIII, FCRIIIA, FCRIIIb, IGFR3, IMD20
Gene ID(Human) 2214,(Human) 2215
Gene symbolFCGR3A, FCGR3B
UniProt ID(Human) P08637,(Human) O75015
Human FCGR3A/CD16A quantitates human FCGR3A/CD16A in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human FCGR3A/CD16A.人FCGR3A / CD16A定量检测血清,血浆,上清液中的人FCGR3A / CD16A。该检测试剂盒将专门识别天然和重组人FCGR3A / CD16A。Target information 靶标信息CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells. Human CD16 is expressed in two forms – FCGR3A and FCGR3B. FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FCGR3A is associated, with FcepsilonRI-beta subunit. Besides IgG, FCGR3A can be triggered also by oligomeric IgE. FCGR3B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a pro-adhesive phenotype. Diseases associated with CD16 dysfunction include immunodeficiency 20 and systemic lupus erythematosus.CD16(FCGR3A)是一种50-65 kDa的细胞表面分子,以两种形式存在-NK细胞和某些T细胞表达的跨膜形式,以及粒细胞表达的磷脂酰肌醇连接形式。 CD16是IgG(FcR III)的低亲和力受体,并且是NK细胞介导ADCC的重要受体。人CD16以两种形式表达-FCGR3A和FCGR3B。 FCGR3A与FcepsilonRI-γ亚基相关,并负责抗体依赖性NK细胞的细胞毒性。肥大细胞FCGR3A与FcepsilonRI-beta亚基相关。除IgG外,FCGR3A也可由寡聚IgE触发。 FCGR3B是在嗜中性粒细胞上表达的GPI连接的单体受体,并参与其活化和诱导前黏附表型。与CD16功能障碍相关的疾病包括免疫缺陷20和系统性红斑狼疮。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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