Human Cystatin SN ELISA Kit ELISA试剂盒,Human Cystatin SN ELISA Kit/人胱抑素SN ELISA试剂盒

2024-10-24

Human Cystatin SN ELISA Kit/人胱抑素SN ELISA试剂盒

货号:EH144RB,EH144RBX5,EH144RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.2 ng/mL

检测范围0.2-50 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCST1
Protein aliasesCystain-SA-I, cystatin 1, cystatin SA-I, Cystatin-1, Cystatin-SN, cysteine proteinase inhibitor, type 2 family, Salivary cystatin-SA-1

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCST1
Gene ID(Human) 1469
Gene symbolCST1
UniProt ID(Human) P01037
Human Cystatin SN quantitates human Cystatin SN in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cystatin SN.人胱抑素SN定量测定血清,血浆,上清液中的人胱抑素SN。该检测试剂盒将专门识别天然和重组人半胱抑素SN。Target information 靶标信息The cystatin superfamily is a well-established family of cysteine protease inhibitors. Cystatins A and B (type 1) are mainly intracellular; cystatins C, D, E/M, F, G, S, SN and SA cystatins are extracellular (type 2); and the kininogens are type 3 cystatins which are intravascular proteins. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, and some also inhibit legumain family enzymes. Cystatin SA, cystatin S and cystatin SN are found primarily in saliva. Cystatin S and SN can also be expressed in tears, urine and seminal fluid. Cystatin C is a related protein which is expressed in brain, thymus, ovary, epididymis and vas deferens. Cystatin D protects against proteinases in the oral cavity, while Cystatin E/M and F moderate the inhibition of cathepsin proteins. The fetuins, part of the cystatin superfamily, are secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors and the response to systemic inflammation. High molecular weight kininogen (Kininogen HC) and low molecular weight kininogen (Kininogen LC) have varied roles, though they both inhibit the thrombin- and plasmin-induced aggregation of thrombocytes.胱抑素超家族是半胱氨酸蛋白酶抑制剂的成熟家族。胱抑素A和B(1型)主要在细胞内。半胱氨酸蛋白酶抑制剂C,D,E / M,F,G,S,SN和SA半胱氨酸蛋白酶抑制剂在细胞外(2型);激肽原是血管内蛋白的3型胱抑素。所有真正的胱抑素都抑制木瓜蛋白酶家族的半胱氨酸肽酶,例如组织蛋白酶,有些还抑制豆蔻蛋白酶家族的酶。胱抑素SA,胱抑素S和胱抑素SN主要存在于唾液中。胱抑素S和SN也可以在眼泪,尿液和精液中表达。胱抑素C是在脑,胸腺,卵巢,附睾和输精管中表达的相关蛋白。胱抑素D保护口腔中的蛋白酶,而胱抑素E / M和F抑制组织蛋白酶的抑制作用。胎蛋白是半胱氨酸蛋白酶抑制剂超家族的一部分,是可分泌的蛋白,它们影响成骨和骨吸收,胰岛素和肝细胞生长因子受体的调节以及对全身炎症的反应。高分子量激肽原(Kininogen HC)和低分子量激肽原(Kininogen LC)具有多种作用,尽管它们都抑制凝血酶和纤溶酶诱导的血小板聚集。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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