LONP1 Polyclonal Antibody

货号：PA5-51692

规格：100 µL

价格：5548

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Recombinant protein corresponding to Human LONP1

物种：人/小鼠/大鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	0.30 mg/mL	用法：	0.25-2 µg/mL(ICC); 0.25-2 µg/mL(IF);1:500-1:1000(IHC);0.04-0.4 µg/mL(WB)

产品详细信息Immunogen sequence: VEEKIKQTHR KYLLQEQLKI IKKELGLEKD DKDAIEEKFR ERLKELVVPK HVMDVVDEEL SKLGLLDNHS SEFNVTRNYL DWLTSIPWGK YSNENLDLAR AQAVLEEDHY GMEDVKKRIL EFIAVSQLRG STQGKILCFY GPHighest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%. 靶标信息This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia. Alternatively spliced transcript variants have been found for this gene.

数据：

LONP1 Antibody (PA5-51692) in IF Immunofluorescent staining of LONP1 in human cell line U-251 MG shows positivity in mitochondria and nucleus but excluded from the nucleoli. Samples were probed using a LONP1 Polyclonal Antibody (Product # PA5-51692). LONP1 Antibody (PA5-51692) in IHC Immunohistochemical staining of LONP1 in human fallopian tube using LONP1 Polyclonal Antibody (Product # PA5-51692) shows granular cytoplasmic positivity in glandular cells. LONP1 Antibody (PA5-51692) in WB Western blot analysis of LONP1 using LONP1 Polyclonal Antibody (Product # PA5-51692 ) (A) shows similar pattern to an independent LONP1 Polyclonal Antibody (B).

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技术参数

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