Human BMPR-II ELISA Kit ELISA试剂盒,Human BMPR-II ELISA Kit/人BMPR-II ELISA试剂盒

2024-10-24

Human BMPR-II ELISA Kit/人BMPR-II ELISA试剂盒

货号:EH50RB,EH50RBX5,EH50RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

2.5 ng/mL

检测范围2.5-600 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameBMPR2
Protein aliasesBMP type II receptor, BMP type-2 receptor, BMPR-2, Bone morphogenetic protein receptor type II, Bone morphogenetic protein receptor type-2, bone morphogenetic protein receptor, type II (serine/threonine kinase), type II activin receptor-like kinase, type II receptor for bone morphogenetic protein-4

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesBMPR-II, BMPR2, BMPR3, BMR2, BRK-3, POVD1, PPH1, T-ALK
Gene ID(Human) 659
Gene symbolBMPR2
UniProt ID(Human) Q13873
Human BMPR-II quantitates human BMPR-II in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human BMPR-II.人BMPR-II定量检测血清,血浆,上清液中的人BMPR-II。该检测试剂盒将专门识别天然和重组人BMPR-II。Target information 靶标信息This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kDa and type II receptors of about 70-80 kDa. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.此基因编码跨膜丝氨酸/苏氨酸激酶的骨形态发生蛋白(BMP)受体家族的成员。该受体的配体是BMP,是TGF-β超家族的成员。 BMPs参与软骨内骨形成和胚胎发生。这些蛋白质通过形成两种不同类型的丝氨酸(苏氨酸)激酶受体的异源复合物来转导其信号:约50-55 kDa的I型受体和约70-80 kDa的II型受体。 II型受体在没有I型受体的情况下结合配体,但它们需要各自的I型受体进行信号传导,而I型受体需要其各自的II型受体进行配体结合。该基因的突变与家族性和芬氟拉明相关的原发性肺动脉高压以及肺静脉闭塞性疾病有关。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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